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PSCA protein, human

Known as: Prostate Antigen, PSCA antigen, human, prostate stem cell antigen, human 
Prostate stem cell antigen (123 aa, ~13 kDa) is encoded by the human PSCA gene. This protein may play a role in the regulation of cell proliferation.
National Institutes of Health

Related topics

Related topics

7 relations
AGS-1C4D4Genes, RegulatorOuter Leaflet of the Lipid BilayerPSCA gene

Broader (3)

Antigens, NeoplasmGPI-Linked ProteinsNeoplasm Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells
Current T-cell engineering approaches redirect patient T cells to tumors by transducing them with antigen-specific T-cell… 
Highly Cited
2009
Highly Cited
2009
Corrigendum: Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer
Nat. Genet. 41, 991–995 (2009); published online 2 August; corrected online 23 August 2009 In the version of this article… 
Highly Cited
2009
Highly Cited
2009
Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer
We conducted a genome-wide association study on 969 bladder cancer cases and 957 controls from Texas. For fast-track validation… 
Highly Cited
2008
Highly Cited
2008
Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer
Gastric cancer is classified into intestinal and diffuse types, the latter including a highly malignant form, linitis plastica. A… 
Highly Cited
2005
Highly Cited
2005
Prostate Stem Cell Antigen Is Overexpressed in Prostate Cancer Metastases
Purpose: Prostate stem cell antigen (PSCA) is expressed by a majority of prostate cancers and is a promising therapeutic target… 
Highly Cited
2001
Highly Cited
2001
Anti-PSCA mAbs inhibit tumor growth and metastasis formation and prolong the survival of mice bearing human prostate cancer xenografts
Prostate stem-cell antigen (PSCA) is a cell-surface antigen expressed in normal prostate and overexpressed in prostate cancer… 
Highly Cited
2000
Highly Cited
2000
Prostate stem cell antigen (PSCA) expression increases with high gleason score, advanced stage and bone metastasis in prostate cancer
Prostate stem cell antigen (PSCA) is a recently defined homologue of the Thy-1/Ly-6 family of glycosylphosphatidylinositol (GPI… 
Highly Cited
1998
Highly Cited
1998
Prostate stem cell antigen: a cell surface marker overexpressed in prostate cancer.
The identification of cell surface antigens is critical to the development of new diagnostic and therapeutic modalities for the… 
Highly Cited
1981
Highly Cited
1981
Prostate antigen: a marker for human prostate epithelial cells.
Specificity of a previously reported prostate antigen (PA) was assessed by several immunologic procedures. This antigen… 
Highly Cited
1979
Highly Cited
1979
Purification of a human prostate specific antigen.
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