PRSS1 protein, human

Known as: TRY1 protein, human, trypsinogen 1 protein, human, trypsin 1 protein, human 
Trypsin-1 (247 aa, ~27 kDa) is encoded by the human PRSS1 gene. This protein is involved in proteolysis.
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Src kinases are activated and relocalize to the cytoplasm during mitosis, but their mitotic function has remained elusive. We… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND & AIMS Hereditary pancreatitis is an autosomal dominant disease that is mostly caused by cationic trypsinogen (PRSS1… (More)
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Highly Cited
2002
Highly Cited
2002
Pancreatitis is a global health care problem with varied aetiologies. Alcoholism is responsible in the majority of patients while… (More)
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Highly Cited
2000
Highly Cited
2000
Membrane-type serine protease 1 (MT-SP1) was recently cloned, and we now report its biochemical characterization. MT-SP1 is… (More)
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Highly Cited
2000
Highly Cited
2000
Chronic pancreatitis (CP) is a continuing or relapsing inflammatory disease of the pancreas. In approximately one-third of all… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND & AIMS Mutations of the cationic trypsinogen have been described in hereditary pancreatitis. We report a new… (More)
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Highly Cited
1999
Highly Cited
1999
Serine proteases of the chymotrypsin fold are of great interest because they provide detailed understanding of their enzymatic… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND & AIMS In pancreatitis, a key role has been attributed to the inappropriate conversion of trypsinogen to trypsin… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND & AIMS We recently identified a single R117H mutation in the cationic trypsinogen gene in several kindreds with an… (More)
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Highly Cited
1996
Highly Cited
1996
Hereditary pancreatitis (HP) is a rare, early-onset genetic disorder characterized by epigastric pain and often more serious… (More)
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