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PREX1 gene

Known as: KIAA1415, phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1, Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 Gene 
This gene is involved in signal transduction.
National Institutes of Health

Papers overview

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2020
2020
BACKGROUND Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 (PREX1) was reported to be overexpressed in… Expand
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2019
2019
Background In previous studies, higher expression of PREX1 (PtdIns (3,4,5)P3-dependent Rac exchanger 1) has been detected in some… Expand
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2017
2017
PREX1 (PtdIns(3,4,5)P3-dependent Rac exchanger 1), is a Rac-GEF overexpressed in a significant proportion of human breast cancers… Expand
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2017
2017
A defining feature of the brain cancer glioblastoma is its highly invasive nature. When glioblastoma cells are isolated from… Expand
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2016
2016
Recently, we identified that PREX1 overexpression is critical for metastatic but not tumorigenic growth in a mouse model of NRAS… Expand
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2016
2016
Downstream of receptor tyrosine kinase and G protein-coupled receptor (GPCR) stimulation, the phosphatidylinositol 3,4,5… Expand
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2015
2015
Pancreatic cancer is the fourth leading cause of cancer death in the Western world. It is a disease of insidious progression and… Expand
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2013
2013
Label-free liquid chromatography-mass spectrometry (LC-MS) quantification methods have been described to determine serum proteins… Expand
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2009
2009
Hypertension is a clinical situation associated with endothelial dysfunction and increased vascular reactive oxygen species (ROS… Expand
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2002
2002
P-Rex1, a novel Rac activator, has been identified in the first biochemical purification of a guanine nucleotide exchange factor… Expand
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