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PP2A-like phosphatases share high homology with PP2A enzymes and are composed of a catalytic subunit and a regulatory subunit. In… Expand DNA-dependent protein kinase (DNA-PK) plays a critical role in DNA damage repair, especially in non-homologous end-joining repair… Expand We recently showed that the gamma-subunit of Kluyveromyces lactis killer toxin (gamma-toxin) is a tRNA endonuclease that cleaves… Expand Protein phosphatase 6 (PP6) is an essential Ser/Thr phosphatase conserved among eukaryotes. The Saccharomyces cerevisiae… Expand The peroxisome, sole site of β-oxidation in Saccharomyces cerevisiae, is known to be required for optimal growth in the presence… Expand Protein Ser/Thr phosphatases compose a PPP family that includes type-2 PP2A, PP4, and PP6, each with essential functions. The… Expand ABSTRACT The Tor kinases are the targets of the immunosuppressive drug rapamycin and couple nutrient availability to cell growth… Expand In order to investigate whether there is a role for individual secreted aspartic proteinases (Saps) of Candida albicans in… Expand We have identified two Saccharomyces cerevisiae genes that, in high copy, confer resistance to Kluyveromyces lactis zymocin, an… Expand Objectives: To assess the relevance of current monitoring alarms as a warning system in the adult ICU. Design: Prospective… Expand