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PPP3CA protein, human

Known as: PPP3CA, Protein Phosphatase 3 Catalytic Subunit Alpha Isoform, protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform protein, human 
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform (521 aa, ~59 kDa) is encoded by the human PPP3CA gene. This protein is… 
National Institutes of Health

Papers overview

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2018
2018
PPP3CA encodes calmodulin-binding catalytic subunit of calcineurin, a ubiquitously expressed calcium/calmodulin-regulated protein… 
2018
2018
Calcineurin is a calcium (Ca2+)/calmodulin-regulated protein phosphatase that mediates Ca2+-dependent signal transduction. Here… 
2017
2017
2017
2017
Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disorder that is associated with repetitive head injury… 
2016
2016
Multiple myeloma (MM) is a relapsed and refractory disease, one that highlights the need for developing new molecular therapies… 
Review
2016
Review
2016
Histone deacetylases (HDACs) critically regulate gene expression by determining the acetylation status of histones. Studies have… 
Highly Cited
2015
Highly Cited
2015
Calcium/calcineurin signaling is critical for normal cellular physiology. Abnormalities in this pathway cause many diseases… 
Highly Cited
2011
Highly Cited
2011
Amyloid-β peptide (Aβ) toxicity and tau hyperphosphorylation are hallmarks of Alzheimer's disease (AD). How their molecular… 
2010
2010
Fine mapping of calcineurin (PPP3CA) gene identified single nucleotide polymorphisms (SNPs) and simple sequence repeat… 
Highly Cited
1996
Highly Cited
1996
Calcineurin (also called protein phosphatase-2B) is a calmodulin-regulated protein phosphatase which plays an important role in…