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PPP2R1B protein, human

Known as: Protein Phosphatase 2 Structural/Regulatory Subunit A Beta, Serine/Threonine-Protein Phosphatase 2A 65 kDa Regulatory Subunit A Beta Isoform, PPP2R1B 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (601 aa, ~66 kDa) is encoded by the human PPP2R1B gene. This protein… 
National Institutes of Health

Related topics

Related topics

5 relations
Cell Proliferation Regulatory ProcessGenes, RegulatorPPP2R1B geneProtein dephosphorylation

Broader (1)

Protein Phosphatase 2A

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Quantitative proteomics reveals novel protein interaction partners of PP2A catalytic subunit in pancreatic β-cells
Highly Cited
2015
Highly Cited
2015
MicroRNA-587 antagonizes 5-FU-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancer
Drug resistance is one of the major hurdles for cancer treatment. However, the underlying mechanisms are still largely unknown… 
2013
2013
Functional Genetic Polymorphisms in PP2A Subunit Genes Confer Increased Risks of Lung Cancer in Southern and Eastern Chinese
Protein phosphatase-2A (PP2A) is one of the major cellular serine-threonine phosphatases and functions as a tumor suppressor that… 
2013
2013
Infrequent mutations of the PPP2R1A and PPP2R1B genes in patients with ovarian cancer.
Protein phosphatase 2, regulatory subunit A, α (PPP2R1A) and β (PPP2R1B) are paralogous subunits of the heterotrimeric protein… 
Highly Cited
2011
Highly Cited
2011
Overexpression of miR-200c Induces Chemoresistance in Esophageal Cancers Mediated Through Activation of the Akt Signaling Pathway
Purpose: To determine the relationship between resistance to chemotherapy and microRNA (miRNA) expression in esophageal cancer… 
Highly Cited
2009
Highly Cited
2009
Two types of human malignant melanoma cell lines revealed by expression patterns of mitochondrial and survival-apoptosis genes: implications for malignant melanoma therapy
Human malignant melanoma has poor prognosis because of resistance to apoptosis and therapy. We describe identification of the… 
2006
2006
The glycine 90 to aspartate alteration in the Aβ subunit of PP2A (PPP2R1B) associates with breast cancer and causes a deficit in protein function
Mutations of the PPP2R1B gene, which encodes the Aβ scaffolding subunit of serine/threonine protein phosphatase 2A (PP2A), have… 
Highly Cited
2004
Highly Cited
2004
PPP2R1B gene alterations inhibit interaction of PP2A-Abeta and PP2A-C proteins in colorectal cancers.
The chromosome region 11q is frequently deleted in colorectal cancers. The PPP2R1B tumor suppressor gene, encoding the beta… 
Highly Cited
2000
Highly Cited
2000
Low frequency of alterations of the α (PPP2R1A) and β (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms
The phosphatase 2A (PP2A) is one of the major cellular serine-threonine phosphatases. It was recently shown that the gene… 
Highly Cited
2000
Highly Cited
2000
Low frequency of alterations of the alpha (PPP2R1A) and beta (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms.
The phosphatase 2A (PP2A) is one of the major cellular serine-threonine phosphatases. It was recently shown that the gene… 
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