PPM1D gene

Known as: PPM1D, protein phosphatase, Mg2+/Mn2+ dependent 1D, wild-type p53-induced phosphatase 1 
This gene plays a role in the modulation of cell cycle arrest.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2018
010203019932018

Papers overview

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Highly Cited
2014
Highly Cited
2014
Several genetic alterations characteristic of leukemia and lymphoma have been detected in the blood of individuals without… (More)
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Highly Cited
2014
Highly Cited
2014
  • The Cancer, Genome Atlas Research Network
  • Cell
  • 2014
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Here, we describe the genomic landscape of 496 PTCs… (More)
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Highly Cited
2013
Highly Cited
2013
Improved sequencing technologies offer unprecedented opportunities for investigating the role of rare genetic variation in common… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE To identify therapeutic targets in ovarian clear cell carcinomas, a chemoresistant and aggressive type of ovarian cancer… (More)
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Highly Cited
2005
Highly Cited
2005
The ATM (ataxia-telangiectasia mutated) and ATR (ataxia-telangiectasia and Rad3-related) kinases respond to DNA damage by… (More)
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Highly Cited
2003
Highly Cited
2003
Neuroblastomas (NBs) show complex patterns of genetic abnormalities, which may include amplification of the MYCN gene, deletion… (More)
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Highly Cited
2002
Highly Cited
2002
Expression of oncogenic Ras in primary human cells activates p53, thereby protecting cells from transformation. We show that in… (More)
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Highly Cited
2002
Highly Cited
2002
We found that PPM1D, encoding a serine/threonine protein phosphatase, lies within an epicenter of the region at 17q23 that is… (More)
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Highly Cited
2000
Highly Cited
2000
The stress-responsive p38 MAPK, when activated by genotoxic stresses such as UV radiation, enhances p53 activity by… (More)
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Highly Cited
1997
Highly Cited
1997
Exposure of mammalian cells to ionizing radiation (IR) induces a complex array of cellular responses including cell cycle arrest… (More)
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