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PPARGC1A protein, human

Known as: PGC-1-Alpha, PPARGC-1-Alpha, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-Alpha 
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (798 aa, ~91 kDa) is encoded by the human PPARGC1A gene. This protein plays a… 
National Institutes of Health

Related topics

Related topics

17 relations
Adipocytokine Signaling PathwayCell NucleusDigestionGenes, Regulator

Broader (1)

Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Long-chain polyunsaturated fatty acids and extensively hydrolyzed casein-induced browning in a Ucp-1 reporter mouse model of obesity.
Browning in adipose tissues, which can be affected by diet, may mitigate the detrimental effects of adiposity and improve longer… 
2018
2018
Effects of long-term exposures to low iron and branched-chain amino acid containing diets on aging skeletal muscle of Fisher 344 × Brown Norway rats.
Aging skeletal muscle displays an altered iron status that may promote oxidative stress and sarcopenia. A diet containing low… 
2017
2017
Intermittent vibration protects aged muscle from mechanical and oxidative damage under prolonged compression.
Review
2017
Review
2017
Ursolic acid: a versatile triterpenoid compound in regulating the aging
We and other studies have elucidated single molecules that can attenuate aging and extend longevity. Indeed, these molecules… 
2017
2017
Trimedazidine alleviates pulmonary artery banding-induced acute right heart dysfunction and activates PRAS40 in rats
The molecular mechanism underlying acute right heart failure (RHF) is poorly understood. We used pulmonary artery banding (PAB… 
2015
2015
Comparative adaptations in oxidative and glycolytic muscle fibers in a low voluntary wheel running rat model performing three levels of physical activity
A unique polygenic model of rat physical activity has been recently developed where rats were selected for the trait of low… 
2012
2012
Targeting mitochondrial biogenesis for promoting health
Summary Mitochondrial biogenesis is a key physiological process that is required for normal growth and development and for… 
2012
2012
Weight Phenotype Diagnostic Test Method: Body Mass Index or Body FatPercent for Gene Expression
Obesity continues increasing at epidemic levels worldwide, as does the number of genetic studies that focus on obesity. Body mass… 
2012
2012
PI 3 K-Akt regulation as a molecular mechanism of the stress response during aerobic dormancy
The biochemical mechanisms that direct intracellular signal transduction networks have been extensively studied in a variety of… 
Highly Cited
2006
Highly Cited
2006
Exercise training decreases the concentration of malonyl-CoA and increases the expression and activity of malonyl-CoA decarboxylase in human muscle.
The study was designed to evaluate whether changes in malonyl-CoA and the enzymes that govern its concentration occur in human… 
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