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PPARGC1A gene

Known as: PPARGC1, PGC1, PPAR-GAMMA COACTIVATOR 1 
This gene plays a role in the regulation of nuclear receptor-dependent transcription.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Irisin was first identified as a peroxisome proliferator-activated receptor γ co-activator-1α (PGC-1α) dependent myokine with the… Expand
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Highly Cited
2009
Highly Cited
2009
Quercetin is one of a broad group of natural polyphenolic flavonoid substances that are being investigated for their widespread… Expand
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Highly Cited
2007
Highly Cited
2007
Aims/hypothesisInsulin secretion in pancreatic islets is dependent upon mitochondrial function and production of ATP. The… Expand
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Highly Cited
2007
Highly Cited
2007
In mammals, maintenance of energy and nutrient homeostasis during food deprivation is accomplished through an increase in… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Caloric restriction without malnutrition extends life span in a range of organisms including insects and mammals and… Expand
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Highly Cited
2005
Highly Cited
2005
Homeostatic mechanisms in mammals respond to hormones and nutrients to maintain blood glucose levels within a narrow range… Expand
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Highly Cited
2003
Highly Cited
2003
Type 2 diabetes mellitus (DM) is characterized by insulin resistance and pancreatic beta cell dysfunction. In high-risk subjects… Expand
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Highly Cited
2003
Highly Cited
2003
Endurance exercise training induces mitochondrial biogenesis in skeletal muscle. The peroxisome proliferator activated receptor… Expand
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Highly Cited
2001
Highly Cited
2001
Blood glucose levels are maintained by the balance between glucose uptake by peripheral tissues and glucose secretion by the… Expand
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Highly Cited
2001
Highly Cited
2001
All nuclear-encoded mRNAs contain a 5′ cap structure (m7GpppN, where N is any nucleotide), which is recognized by the eukaryotic… Expand
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