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POLYCYSTIC KIDNEY DISEASE 3, AUTOSOMAL DOMINANT

Known as: POLYCYSTIC KIDNEY DISEASE, ADULT, TYPE III, APKD3, POLYCYSTIC KIDNEY DISEASE 3 
National Institutes of Health

Related topics

Related topics

3 relations
Autosomal dominant inheritanceHepatic cystsRenal cyst

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Evidence of a third ADPKD locus is not supported by reanalysis of designated PKD3 families
Mutations to PKD1 and PKD2 are associated with autosomal dominant polycystic kidney disease (ADPKD). The absence of apparent PKD1… Expand
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2009
2009
PKD3 Is the Predominant Protein Kinase D Isoform in Mouse Exocrine Pancreas and Promotes Hormone-induced Amylase Secretion*
The protein kinase D (PKD) family of serine/threonine kinases, which can be activated by gastrointestinal hormones, consists of… Expand
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2008
2008
Expression patterns of protein kinase D 3 during mouse development
BackgroundThe PKD family of serine/threonine kinases comprises a single member in Drosophila (dPKD), two isoforms in C. elegans… Expand
Highly Cited
2007
Highly Cited
2007
A Novel Tyrosine Phosphorylation Site in Protein Kinase D Contributes to Oxidative Stress-mediated Activation*
Protein kinase D1 (PKD1) is a mediator of oxidative stress signaling where it regulates cellular detoxification and survival… Expand
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Highly Cited
2006
Highly Cited
2006
Essential Role for Protein Kinase D Family Kinases in the Regulation of Class II Histone Deacetylases in B Lymphocytes
ABSTRACT We have taken a knockout approach to interrogate the function of protein kinase D (PKD) serine/threonine kinases in… Expand
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Highly Cited
2006
Highly Cited
2006
Protein Kinase D Intracellular Localization and Activity Control Kinase D-interacting Substrate of 220-kDa Traffic through a Postsynaptic Density-95/Discs Large/Zonula Occludens-1-binding Motif*
Protein kinase D (PKD) controls protein traffic from the trans-Golgi network (TGN) to the plasma membrane of epithelial cells in… Expand
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Highly Cited
2005
Highly Cited
2005
Protein Kinase C-Independent Effects of Protein Kinase D3 in Glucose Transport in L6 Myotubes
Protein kinase C (PKC) and protein kinase D (PKD) coordinate and regulate many fundamental cellular processes. In this study, we… Expand
Highly Cited
2003
Highly Cited
2003
Protein Kinase Cν/Protein Kinase D3 Nuclear Localization, Catalytic Activation, and Intracellular Redistribution in Response to G Protein-coupled Receptor Agonists*
The protein kinase D (PKD) family consists of three serine/threonine kinases: PKCμ/PKD, PKD2, and PKCν/PKD3. Whereas PKD has been… Expand
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Review
2000
Review
2000
Autosomal dominant polycystic kidney disease: molecular genetics and molecular pathogenesis
Abstract. Mutations in three different genes, PKD1, PKD2 and PKD3, can cause a very similar clinical picture of the autosomal… Expand
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1998
1998
Is there a third gene for autosomal dominant polycystic kidney disease?
Autosomal dominant polycystic kidney disease (ADPKD) is a common Mendelian disorder. Linkage studies have estimated that 80 to 85… Expand
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