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POLYCYSTIC KIDNEY DISEASE 3, AUTOSOMAL DOMINANT
Known as:
POLYCYSTIC KIDNEY DISEASE, ADULT, TYPE III
, APKD3
, POLYCYSTIC KIDNEY DISEASE 3
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National Institutes of Health
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Related topics
Related topics
3 relations
Autosomal dominant inheritance
Hepatic cysts
Renal cyst
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Protein Kinase D Enzymes as Regulators of EMT and Cancer Cell Invasion
N. Durand
,
Sahra Borgés
,
P. Storz
Journal of clinical medicine
2016
Corpus ID: 7692365
The Protein Kinase D (PKD) isoforms PKD1, PKD2, and PKD3 are effectors of the novel Protein Kinase Cs (nPKCs) and diacylglycerol…
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2015
2015
SD-208, a Novel Protein Kinase D Inhibitor, Blocks Prostate Cancer Cell Proliferation and Tumor Growth In Vivo by Inducing G2/M Cell Cycle Arrest
M. Tandon
,
Joseph M. Salamoun
,
+6 authors
Q. J. Wang
PloS one
2015
Corpus ID: 16670640
Protein kinase D (PKD) has been implicated in many aspects of tumorigenesis and progression, and is an emerging molecular target…
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2008
2008
Expression patterns of protein kinase D 3 during mouse development
Kornelia Ellwanger
,
K. Pfizenmaier
,
S. Lutz
,
A. Hausser
BMC Developmental Biology
2008
Corpus ID: 4146247
BackgroundThe PKD family of serine/threonine kinases comprises a single member in Drosophila (dPKD), two isoforms in C. elegans…
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Highly Cited
2007
Highly Cited
2007
A Novel Tyrosine Phosphorylation Site in Protein Kinase D Contributes to Oxidative Stress-mediated Activation*
H. Döppler
,
P. Storz
Journal of Biological Chemistry
2007
Corpus ID: 22084221
Protein kinase D1 (PKD1) is a mediator of oxidative stress signaling where it regulates cellular detoxification and survival…
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Highly Cited
2006
Highly Cited
2006
Essential Role for Protein Kinase D Family Kinases in the Regulation of Class II Histone Deacetylases in B Lymphocytes
S. Matthews
,
Ping Liu
,
+4 authors
A. Scharenberg
Molecular and Cellular Biology
2006
Corpus ID: 20324638
ABSTRACT We have taken a knockout approach to interrogate the function of protein kinase D (PKD) serine/threonine kinases in…
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Highly Cited
2006
Highly Cited
2006
Protein Kinase D Intracellular Localization and Activity Control Kinase D-interacting Substrate of 220-kDa Traffic through a Postsynaptic Density-95/Discs Large/Zonula Occludens-1-binding Motif*
Lucía Sánchez-Ruiloba
,
N. Cabrera-Poch
,
+4 authors
T. Iglesias
Journal of Biological Chemistry
2006
Corpus ID: 22141887
Protein kinase D (PKD) controls protein traffic from the trans-Golgi network (TGN) to the plasma membrane of epithelial cells in…
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Highly Cited
2005
Highly Cited
2005
Protein Kinase C-Independent Effects of Protein Kinase D3 in Glucose Transport in L6 Myotubes
Jun Chen
,
Ganwei Lu
,
Q. J. Wang
Molecular Pharmacology
2005
Corpus ID: 24082021
Protein kinase C (PKC) and protein kinase D (PKD) coordinate and regulate many fundamental cellular processes. In this study, we…
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Highly Cited
2003
Highly Cited
2003
Protein Kinase Cν/Protein Kinase D3 Nuclear Localization, Catalytic Activation, and Intracellular Redistribution in Response to G Protein-coupled Receptor Agonists*
O. Rey
,
Jingzhen Yuan
,
S. H. Young
,
E. Rozengurt
Journal of Biological Chemistry
2003
Corpus ID: 25301373
The protein kinase D (PKD) family consists of three serine/threonine kinases: PKCμ/PKD, PKD2, and PKCν/PKD3. Whereas PKD has been…
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Review
2000
Review
2000
Autosomal dominant polycystic kidney disease: molecular genetics and molecular pathogenesis
M. Koptides
,
C. Deltas
Human Genetics
2000
Corpus ID: 11284208
Abstract. Mutations in three different genes, PKD1, PKD2 and PKD3, can cause a very similar clinical picture of the autosomal…
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1998
1998
Is there a third gene for autosomal dominant polycystic kidney disease?
A. Paterson
,
Y. Pei
Kidney international
1998
Corpus ID: 19678213
Autosomal dominant polycystic kidney disease (ADPKD) is a common Mendelian disorder. Linkage studies have estimated that 80 to 85…
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