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POLYCYSTIC KIDNEY DISEASE 3, AUTOSOMAL DOMINANT

Known as: POLYCYSTIC KIDNEY DISEASE, ADULT, TYPE III, APKD3, POLYCYSTIC KIDNEY DISEASE 3 
National Institutes of Health

Related topics

Related topics

3 relations
Autosomal dominant inheritanceHepatic cystsRenal cyst

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Protein Kinase D Enzymes as Regulators of EMT and Cancer Cell Invasion
The Protein Kinase D (PKD) isoforms PKD1, PKD2, and PKD3 are effectors of the novel Protein Kinase Cs (nPKCs) and diacylglycerol… 
2015
2015
SD-208, a Novel Protein Kinase D Inhibitor, Blocks Prostate Cancer Cell Proliferation and Tumor Growth In Vivo by Inducing G2/M Cell Cycle Arrest
Protein kinase D (PKD) has been implicated in many aspects of tumorigenesis and progression, and is an emerging molecular target… 
2008
2008
Expression patterns of protein kinase D 3 during mouse development
BackgroundThe PKD family of serine/threonine kinases comprises a single member in Drosophila (dPKD), two isoforms in C. elegans… 
Highly Cited
2007
Highly Cited
2007
A Novel Tyrosine Phosphorylation Site in Protein Kinase D Contributes to Oxidative Stress-mediated Activation*
Protein kinase D1 (PKD1) is a mediator of oxidative stress signaling where it regulates cellular detoxification and survival… 
Highly Cited
2006
Highly Cited
2006
Essential Role for Protein Kinase D Family Kinases in the Regulation of Class II Histone Deacetylases in B Lymphocytes
ABSTRACT We have taken a knockout approach to interrogate the function of protein kinase D (PKD) serine/threonine kinases in… 
Highly Cited
2006
Highly Cited
2006
Protein Kinase D Intracellular Localization and Activity Control Kinase D-interacting Substrate of 220-kDa Traffic through a Postsynaptic Density-95/Discs Large/Zonula Occludens-1-binding Motif*
Protein kinase D (PKD) controls protein traffic from the trans-Golgi network (TGN) to the plasma membrane of epithelial cells in… 
Highly Cited
2005
Highly Cited
2005
Protein Kinase C-Independent Effects of Protein Kinase D3 in Glucose Transport in L6 Myotubes
Protein kinase C (PKC) and protein kinase D (PKD) coordinate and regulate many fundamental cellular processes. In this study, we… 
Highly Cited
2003
Highly Cited
2003
Protein Kinase Cν/Protein Kinase D3 Nuclear Localization, Catalytic Activation, and Intracellular Redistribution in Response to G Protein-coupled Receptor Agonists*
The protein kinase D (PKD) family consists of three serine/threonine kinases: PKCμ/PKD, PKD2, and PKCν/PKD3. Whereas PKD has been… 
Review
2000
Review
2000
Autosomal dominant polycystic kidney disease: molecular genetics and molecular pathogenesis
Abstract. Mutations in three different genes, PKD1, PKD2 and PKD3, can cause a very similar clinical picture of the autosomal… 
1998
1998
Is there a third gene for autosomal dominant polycystic kidney disease?
Autosomal dominant polycystic kidney disease (ADPKD) is a common Mendelian disorder. Linkage studies have estimated that 80 to 85… 
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