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PNU 159548
Known as:
PNU-159548
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
4-Demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548): a promising new candidate for chemotherapeutic treatment of osteosarcoma patients.
M. Pasello
,
C. Hattinger
,
+7 authors
M. Serra
European journal of cancer
2005
Corpus ID: 5799694
The effectiveness of the alkycycline 4-demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548…
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2003
2003
Predicting the maximum-tolerated dose of PNU-159548 (4-demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin) in humans using CFU-GM clonogenic assays and prospective validation.
D. Moneta
,
C. Geroni
,
+6 authors
C. Sessa
European journal of cancer
2003
Corpus ID: 20391748
A haematotoxicity model was proposed by Parchment in 1998 to predict the maximum-tolerated dose (MTD) in humans of…
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2002
2002
Phase I and pharmacokinetic studies of PNU-159548, a novel alkycycline, administered intravenously to patients with advanced solid tumours.
M. D. de Jonge
,
J. Verweij
,
+9 authors
C. Sessa
European journal of cancer
2002
Corpus ID: 23930280
PNU-159548 (4-demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin) is the lead compound of a novel class of…
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2001
2001
Pharmacological and toxicological aspects of 4-demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548): a novel antineoplastic agent.
C. Geroni
,
M. Ripamonti
,
+10 authors
M. Caruso
Cancer research
2001
Corpus ID: 22167228
4-demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548) belongs to a novel class of antitumor compounds…
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2001
2001
4-Demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548), a novel anticancer agent active against tumor cell lines with different resistance mechanisms.
S. Marchini
,
G. Damia
,
+4 authors
C. Geroni
Cancer research
2001
Corpus ID: 25027145
The activity of 4-demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548), a new alkycycline with high…
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2001
2001
PNU-159548, a novel cytotoxic antitumor agent with a low cardiotoxic potential
P. Della Torre
,
A. Podestà
,
+5 authors
M. Brughera
Cancer Chemotherapy and Pharmacology
2001
Corpus ID: 25673310
Purpose: PNU-159548 (4-demethoxy-3'-deamino-3'aziridinyl-4'-methylsulphonyl-daunorubicin), a derivative of the anticancer…
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2001
2001
Pharmacological and Toxicological Aspects of 4-Demethoxy-3 *-deamino-3 *-aziridinyl-4 *-methylsulphonyl-daunorubicin ( PNU-159548 ) : A Novel Antineoplastic Agent 1
C. Geroni
,
M. Ripamonti
,
+10 authors
M. Caruso
2001
Corpus ID: 19378912
4-demethoxy-3*-deamino-3*-aziridinyl-4*-methylsulphonyl-daunorubicin (PNU-159548) belongs to a novel class of antitumor compounds…
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1999
1999
Determination of 4-demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyldaunorubicin+ ++ and its 13-hydroxy metabolite by direct injection of human plasma into a column-switching liquid…
M. Breda
,
G. Basileo
,
G. Fonte
,
J. Long
,
C. James
Journal of chromatography. A
1999
Corpus ID: 23791306
A selective, sensitive and fully automated column-switching LC system using direct injection of human plasma followed by mass…
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