Skip to search formSkip to main contentSkip to account menu

PMS2 protein, human

Known as: PMS2, EC 3.1.-.-, hPMS2 protein, human 
Mismatch repair endonuclease PMS2 (862 aa, ~96 kDa) is encoded by the human PMS2 gene. This protein plays a role in DNA mismatch repair.
National Institutes of Health

Related topics

Related topics

18 relations
Cell NucleusDNA RepairDNA Repair EndonucleaseDNA Repair Gene

Broader (1)

Mismatch repair endonuclease PMS2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Importance of genetic testing for patients with multiple colorectal cancer primaries.
528Background: Individuals with hereditary colorectal cancer (CRC) may be at increased risk for a second primary CRC. Therefore… 
2016
2016
ИММУНОГИСТОХИМИЧЕСКОЕ ИССЛЕДОВАНИЕ MSH2, MSH6, PMS2, MLH1 В ОПРЕДЕЛЕНИИ СТЕПЕНИ ЗЛОКАЧЕСТВЕННОСТИ АДЕНОКАРЦИНОМЫ ТОЛСТОЙ КИШКИ
Microsatellite instability is associated with dysfunction of the MSH2, MLH1, PMS2 and MSH6 genes, which participate in the repair… 
2014
2014
Somatic Hypermutation at A/T-Rich Oligonucleotide Substrates Shows Different Strand Polarities in Ung-Deficient or -Proficient Backgrounds
ABSTRACT A/T mutations at immunoglobulin loci are introduced by DNA polymerase η (Polη) during an Msh2/6-dependent repair process… 
2011
2011
FREQUÊNCIA DE MUTAÇÕES NOS GENES MSH6, PMS1, PMS2, TP53 E CHEK2 EM PACIENTES SUSPEITOS DE SÍNDROME DE LYNCH
1999
1999
Transgenic expression of human MGMT blocks the hypersensitivity of PMS2-deficient mice to low dose MNU thymic lymphomagenesis.
Mice deficient in the DNA mismatch repair (MMR) gene, PMS2, develop spontaneous thymic lymphomas and sarcomas. We have previously… 
1999
1999
PMS2-deficiency diminishes hypermutation of a lambda1 transgene in young but not older mice.
The Pms2 gene is involved in DNA mismatch repair in mammalian cells, and has recently been shown to affect hypermutation of… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)