PLA2R1 gene

Known as: PLA2R, Phospholipase A2 Receptor 1, 180kDa Gene, PLA2R1 
This gene plays a role in the localization of phospholipases.
National Institutes of Health

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Induction of Cell SenescenceLigand BindingPLA2R1 protein, humanPhospholipases A2
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Papers overview

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2014
2014
Association of anti-PLAâ‚‚R antibodies with outcomes after immunosuppressive therapy in idiopathic membranous nephropathy.
BACKGROUND The optimal timing and duration of immunosuppressive therapy for idiopathic membranous nephropathy (iMN) have been… (More)
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2014
2014
HLA-DQA1 and PLA2R1 polymorphisms and risk of idiopathic membranous nephropathy.
BACKGROUND AND OBJECTIVES Single nucleotide polymorphisms (SNPs) within HLA complex class II HLA-DQ α-chain 1 (HLA-DQA1) and M… (More)
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2014
2014
PLA2R-associated membranous glomerulopathy is modulated by common variants in PLA2R1 and HLA-DQA1 genes
Membranous glomerulopathy (MG) is most commonly caused by autoantibodies directed against the podocyte phospholipase A2 receptor… (More)
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2014
2014
The Diagnosis Accuracy of PLA2R-AB in the Diagnosis of Idiopathic Membranous Nephropathy: A Meta-Analysis
BACKGROUND The presence of antibodies against the M-type phospholipase A2 receptor (PLA2R-AB) is considered to be a promising… (More)
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2013
2013
Interaction between PLA2R1 and HLA-DQA1 variants associates with anti-PLA2R antibodies and membranous nephropathy.
Risk alleles at genome loci containing phospholipase A2 receptor 1 (PLA2R1) and HLA-DQA1 closely associate with idiopathic… (More)
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2013
2013
Determination of primary versus secondary membranous glomerulopathy utilizing phospholipase A2 receptor staining in renal biopsies
Autoantibody formation directed against phospholipase A2 receptor (PLA2R)1 is the underlying etiology in most cases of primary… (More)
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2013
2013
Phospholipase A2 receptor (PLA2R1) sequence variants in idiopathic membranous nephropathy.
The M-type receptor for phospholipase A2 (PLA2R1) is the major target antigen in idiopathic membranous nephropathy (iMN). Our… (More)
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Highly Cited
2011
Highly Cited
2011
PLA2R autoantibodies and PLA2R glomerular deposits in membranous nephropathy.
n engl j med 364;7 nejm.org february 17, 2011 689 1. Flieger D, Hainke S, Fischbach W. Dramatic improvement in hereditary… (More)
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Highly Cited
2011
Highly Cited
2011
Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.
BACKGROUND Idiopathic membranous nephropathy is a major cause of the nephrotic syndrome in adults, but its etiologic basis is not… (More)
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2010
2010
Systematic Analysis of a Novel Human Renal Glomerulus-Enriched Gene Expression Dataset
Glomerular diseases account for the majority of cases with chronic renal failure. Several genes have been identified with key… (More)
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