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PK1 doxorubicin-HPMA conjugate

Known as: PK1 
 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Phase I studies of [N-(2-hydroxypropyl)methacrylamide] (HPMA) copolymer-doxorubicin previously showed signs of activity coupled… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT Gentamicin accumulates in the lysosomes of kidney proximal tubular cells and causes apoptosis at clinically relevant… Expand
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Highly Cited
2004
Highly Cited
2004
This study investigated the possible role of the newly discovered endocrine gland-derived vascular endothelial growth factors and… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Induction of heme oxygenase-1 (HO-1) protects against diverse insults in the kidney and other tissues. We examined the… Expand
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Highly Cited
2000
Highly Cited
2000
Human pancreatic adenocarcinoma cell lines PK1 and PK8 are resistant to the clinically relevant chemotherapy agent gemcitabine… Expand
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Highly Cited
1999
Highly Cited
1999
PK1 comprises doxorubicin covalently bound to N -(2-hydroxypropyl)methacrylamide copolymer by a peptidyl linker. Following… Expand
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Highly Cited
1999
Highly Cited
1999
PK1 comprises doxorubicin covalently bound to N-(2-hydroxypropyl)methacrylamide copolymer by a peptidyl linker. Following… Expand
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Highly Cited
1994
Highly Cited
1994
1 SB 200646A, N‐(1‐methyl‐5‐indolyl)‐N′‐(3‐pyridyl) urea hydrochloride, the first reported selective 5‐HT2C/2B over 5‐HT2A… Expand
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Highly Cited
1994
Highly Cited
1994
Previously, we have shown that liposomal amphotericin B (L-AmpB) composed of dimyristoylphosphatidylcholine (DMPC) and… Expand
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Highly Cited
1985
Highly Cited
1985
The expression of enzymes in LLC-PK1 and MDCK cells was used to study the retention of differentiated properties of the renal… Expand
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