PK1 doxorubicin-HPMA conjugate

Known as: PK1 
 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Phase I studies of [N-(2-hydroxypropyl)methacrylamide] (HPMA) copolymer-doxorubicin previously showed signs of activity coupled… (More)
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Highly Cited
2004
Highly Cited
2004
This study investigated the possible role of the newly discovered endocrine gland-derived vascular endothelial growth factors and… (More)
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2001
2001
BACKGROUND Induction of heme oxygenase-1 (HO-1) protects against diverse insults in the kidney and other tissues. We examined the… (More)
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Highly Cited
2000
Highly Cited
2000
Human pancreatic adenocarcinoma cell lines PK1 and PK8 are resistant to the clinically relevant chemotherapy agent gemcitabine… (More)
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Highly Cited
1999
Highly Cited
1999
PK1 comprises doxorubicin covalently bound to N-(2-hydroxypropyl)methacrylamide copolymer by a peptidyl linker. Following… (More)
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1999
1999
PK1 is a synthetic N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin (dox) conjugate currently undergoing Phase II… (More)
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1998
1998
N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-doxorubicin (PK1) is a novel polymeric anticancer agent containing doxorubicin… (More)
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1998
1998
The present study was aimed at the uptake of L-3,4-dihydroxyphenylalanine (L-dopa) and its intracellular decarboxylation to… (More)
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1994
1994
1. SB 200646A, N-(1-methyl-5-indolyl)-N'-(3-pyridyl) urea hydrochloride, the first reported selective 5-HT2C/2B over 5-HT2A… (More)
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