PIK3CG protein, human

Known as: PI3-Kinase Subunit Gamma, PtdIns-3-Kinase p110, PIK3CG 
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (1102 aa, ~126 kDa) is encoded by the human PIK3CG gene. This protein… (More)
National Institutes of Health

Papers overview

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2010
2010
High mobility group box 1 (HMGB1) is an alarmin actively secreted by immune cells and passively released by necrotic nonimmune… (More)
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2009
2009
Phosphatidylinositol 3-kinase (PI3K) isoforms PI3Kbeta and PI3Kgamma are implicated in platelet adhesion, activation, and… (More)
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2008
2008
Ischemic preconditioning (IPC) is a potent cellular protective mechanism whereby brief periods of sublethal ischemia protect the… (More)
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2007
2007
Use of mice in which individual PI3K isoforms have been deleted or mutated by gene targeting, has determined that PI3Kgamma… (More)
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Highly Cited
2006
Highly Cited
2006
Phosphoinositide 3-kinase (PI3K) gamma has been implicated in a vast array of physiological settings including the activation of… (More)
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2005
2005
Stimulation of platelet G protein-coupled receptors results in the cleavage of phosphatidylinositol 4,5-trisphosphate (PIP(2… (More)
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2003
Highly Cited
2003
Thromboxane A2 (TXA2)-mediated platelet secretion and aggregation are important in thrombosis. Here, we present a novel finding… (More)
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2002
2002
BACKGROUND Type I phosphoinositide 3-kinases are responsible for the hormone-sensitive synthesis of the lipid messenger… (More)
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Highly Cited
2001
Highly Cited
2001
Platelet aggregation and subsequent thrombosis are the major cause of ischemic diseases such as heart attack and stroke. ADP… (More)
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Highly Cited
1998
Highly Cited
1998
Phosphoinositide 3-kinases (PI3Ks) activate protein kinase PKB (also termed Akt), and PI3Kgamma activated by heterotrimeric… (More)
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