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PHA 408
Known as:
PHA-408
, PHA408
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Indazoles
Isonicotinic Acids
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Essential role of STAT-3 dependent NF-κB activation on IL-6-mediated downregulation of hepatic transporters.
Walaa A. Abualsunun
,
Ç. Şahi̇n
,
C. Cummins
,
M. Piquette-Miller
European Journal of Pharmaceutical Sciences
2019
Corpus ID: 208165684
Highly Cited
2017
Highly Cited
2017
Premature senescence of endothelial cells upon chronic exposure to TNFα can be prevented by N-acetyl cysteine and plumericin
S. Khan
,
E. Awad
,
+7 authors
J. Breuss
Scientific Reports
2017
Corpus ID: 23637184
Cellular senescence is characterized by a permanent cell-cycle arrest and a pro-inflammatory secretory phenotype, and can be…
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2017
2017
Involvement of Nuclear Factor κB, not Pregnane X Receptor, in Inflammation-Mediated Regulation of Hepatic Transporters
Walaa A. Abualsunun
,
M. Piquette-Miller
Drug Metabolism And Disposition
2017
Corpus ID: 206499395
Endotoxin-induced inflammation decreases the hepatic expression of several drug transporters, metabolizing enzymes, and nuclear…
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Review
2017
Review
2017
Natural Modulators of Endosomal Toll-Like Receptor-Mediated Psoriatic Skin Inflammation
Chao-Yang Lai
,
Yu-Wen Su
,
Kuo-I Lin
,
L. Hsu
,
T. Chuang
Journal of Immunological Research
2017
Corpus ID: 6090688
Psoriasis is a chronic inflammatory autoimmune disease that can be initiated by excessive activation of endosomal toll-like…
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2015
2015
The effect of specific IKKβ inhibitors on the cytosolic expression of IκB-α and the nuclear expression of p65 in dystrophic (MDX) muscle.
C. Carlson
,
E. Dole
,
C. Stefanski
,
David S. Bayless
American journal of translational research
2015
Corpus ID: 32992853
The efficacy of two highly specific IκB-α kinase β (IKK-β) inhibitors in reducing the enhanced basal activation of the NF-κB…
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Review
2013
Review
2013
Toll-like receptors as therapeutic targets for autoimmune connective tissue diseases.
Jing Li
,
Xiaohui Wang
,
Fengchun Zhang
,
H. Yin
Pharmacology and Therapeutics
2013
Corpus ID: 3267948
2010
2010
Anti-inflammatory effect of a selective IkappaB kinase-beta inhibitor in rat lung in response to LPS and cigarette smoke.
S. Rajendrasozhan
,
Jae-woong Hwang
,
H. Yao
,
N. Kishore
,
I. Rahman
Pulmonary Pharmacology & Therapeutics
2010
Corpus ID: 34931496
2010
2010
Expression, purification and functional characterization of IkappaB kinase-2 (IKK-2) mutants.
S. Mathialagan
,
G. Poda
,
+6 authors
G. Mbalaviele
Protein Expression and Purification
2010
Corpus ID: 7862699
Highly Cited
2009
Highly Cited
2009
A Novel, Highly Selective, Tight Binding IκB Kinase-2 (IKK-2) Inhibitor: A Tool to Correlate IKK-2 Activity to the Fate and Functions of the Components of the Nuclear Factor-κB Pathway in Arthritis…
G. Mbalaviele
,
C. Sommers
,
+11 authors
N. Kishore
Journal of Pharmacology and Experimental…
2009
Corpus ID: 23587308
Nuclear factor (NF)-κB activation has been clearly linked to the pathogenesis of multiple inflammatory diseases including…
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2009
2009
Novel Tight-Binding Inhibitory Factor-κB Kinase (IKK-2) Inhibitors Demonstrate Target-Specific Anti-Inflammatory Activities in Cellular Assays and following Oral and Local Delivery in an in Vivo…
C. Sommers
,
J. Thompson
,
+14 authors
N. Kishore
Journal of Pharmacology and Experimental…
2009
Corpus ID: 10628730
Nuclear factor-κB (NF-κB) is one of the major families of transcription factors activated during the inflammatory response in…
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