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PHA 408

Known as: PHA-408, PHA408 
 
National Institutes of Health

Papers overview

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2019
2019
IL-6 markedly decreases the expression of numerous hepatic transporters. We previously demonstrated that IL-6-mediated… Expand
2017
2017
Endotoxin-induced inflammation decreases the hepatic expression of several drug transporters, metabolizing enzymes, and nuclear… Expand
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2017
2017
Cellular senescence is characterized by a permanent cell-cycle arrest and a pro-inflammatory secretory phenotype, and can be… Expand
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Review
2017
Review
2017
Psoriasis is a chronic inflammatory autoimmune disease that can be initiated by excessive activation of endosomal toll-like… Expand
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2015
2015
The efficacy of two highly specific IκB-α kinase β (IKK-β) inhibitors in reducing the enhanced basal activation of the NF-κB… Expand
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2010
2010
RATIONALE IkappaB kinase (IKK) activates NF-kappaB which plays a pivotal role in pro-inflammatory response in the lung. NF-kappaB… Expand
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2010
2010
NF-kappaB activation is clearly linked to the pathogenesis of multiple inflammatory diseases including arthritis. The prominent… Expand
2010
2010
NF-kappaB signaling plays a pivotal role in a variety of pathological conditions. Because of its central role in the overall NF… Expand
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Highly Cited
2009
Highly Cited
2009
Nuclear factor (NF)-κB activation has been clearly linked to the pathogenesis of multiple inflammatory diseases including… Expand
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2009
2009
Nuclear factor-κB (NF-κB) is one of the major families of transcription factors activated during the inflammatory response in… Expand
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