PDPK1 wt Allele

Known as: 3-Phosphoinositide Dependent Protein Kinase-1 wt Allele, PDK1, PRO0461 
Human PDPK1 wild-type allele is located in the vicinity of 16p13.3 and is approximately 63 kb in length. This allele, which encodes 3… (More)
National Institutes of Health

Papers overview

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2013
2013
Glioblastoma multiforme is the most aggressive primary brain tumor in adults. Overexpression of the EGF receptor (EGFR) is… (More)
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2013
2013
The effects of phosphoinositide-dependent protein kinase 1 (PDK1), a master kinase in the phosphoinositide 3-kinase/Akt pathway… (More)
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2012
2012
Mutations leading to inappropriate activation of Akt isoforms contribute to proliferation and survival of a significant… (More)
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Highly Cited
2010
Highly Cited
2010
We investigated expression profiles of microRNA (miRNA) in gastric carcinomas by use of a miRNA microarray platform covering a… (More)
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Review
2008
Review
2008
Signal transduction of many growth factors and oncogenes is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1), a… (More)
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Highly Cited
1999
Highly Cited
1999
Rapamycin is an immunosuppressant which antagonizes cellular proliferation by inhibiting the function of mTOR. The mTOR : FKBP12… (More)
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Highly Cited
1998
Highly Cited
1998
Activation of the protein p70s6k by mitogens leads to increased translation of a family of messenger RNAs that encode essential… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND The p70 S6 kinase, an enzyme critical for cell-cycle progression through the G1 phase, is activated in vivo by insulin… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND The activation of protein kinase B (PKB, also known as c-Akt) is stimulated by insulin or growth factors and results… (More)
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