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PDPK1 wt Allele

Known as: 3-Phosphoinositide Dependent Protein Kinase-1 wt Allele, PDK1, PRO0461 
Human PDPK1 wild-type allele is located in the vicinity of 16p13.3 and is approximately 63 kb in length. This allele, which encodes 3… 
National Institutes of Health

Related topics

Related topics

28 relations
16p13.3AKT Signaling PathwayAngiogenesis PathwayB Cell Receptor Signaling Pathway

Broader (1)

PDPK1 gene

Papers overview

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2018
2018
PDK1在内皮细胞向造血细胞转换中的作用研究
目的 研究磷酸肌醇依赖性激酶1（PDK1）在内皮细胞向造血细胞转化阶段对造血干细胞（HSC）发生的影响。 方法 应用Vec-Cre在内皮细胞中特异性敲除PDK1基因，取对照组PDK1fl/fl、PDK1fl/+小鼠及敲除组Vec-Cre；PDK1fl/fl… 
2016
2016
Corrigendum The hVps 34-SGK 3 pathway alleviates sustained PI 3 K / Akt inhibition by stimulating mTORC 1 and tumour growth
We would like to apologise for the oversight in not referring to another recently published study that some of us co-authored… 
2014
2014
PDK 1 regulates focal adhesion disassembly through modulation of 1 v 3 integrin endocytosis
v3 integrin endocytosis 2 3 Laura di Blasio 1,2,* , Paolo Armando Gagliardi 1,2 , Alberto Puliafito 1,2 , Roberto Sessa 4 1,2,3… 
2013
2013
PLATELETS AND THROMBOPOIESIS PDK 1 regulates platelet activation and arterial thrombosis
Platelets, which are derived from megakaryocytes, circulate in mammalian blood and play essential roles in hemostasis… 
2013
2013
Abstract 1215: Loss of PTEN expression predicts poor prognosis in patients with intraductal papillary mucinous neoplasms of the pancreas.
Purpose: Previously we have reported PIK3CA gene mutations in high-grade intraductal papillary mucinous neoplasms (IPMNs… 
2012
2012
Induced PDK1 kinase activity suppresses apoptosis in intestinal epithelial cells by activating Akt signaling following polyamine depletion.
Apoptosis plays a critical role in the maintenance of gut mucosal homeostasis and is highly regulated by numerous factors… 
2011
2011
Inhibiteurs n-phénylimidazolecarboxamides de la protéine kinase 3-phosphoinositide-dépendante de type 1
La presente invention porte sur des composes imidazolecarboxamides de formule (I) : (I), dans laquelle D, T, R1, R2, R3 et R6… 
2007
2007
Restoration of glucokinase expression in the liver normalizes postprandial glucose disposal in mice with hepatic deficiency of PDK1
2006
2006
PDK1-mediated IKKβ phosphorylation activates NF-κB signaling
4837 The IκB kinase (IKK)/NF-κB and phosphatidylinositol-3-OH kinase (PI3K)/3-phosphoinositide-dependent protein kinase-1 (PDK1… 
2002
2002
Associated with the Induction of Protein Kinase C 3-Phosphoinositide-dependent Protein Kinase-1 ( PDK 1 ) Is Transformation of Mammary Epithelial Cells by Updated
3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a mediator of multiple signaling pathways coupled to growth factor… 
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