PDGF-DD-receptor beta complex
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Many tumors produce platelet-derived growth factor (PDGF)-DD, which promotes cellular proliferation, epithelial-mesenchymal… Expand In addition to exogenous ligands derived from pathogens, natural killer (NK) and other innate cells can recognize endogenous… Expand Significance Emerging evidence suggest that the cellular composition of tumors is highly heterogeneous. Subclonal species of… Expand Tumors are complex entities, composed of different functional populations of malignant and stromal cells. There is an emerging… Expand Members of the platelet-derived growth factor (PDGF) family are mitogens for cells of a mesenchymal origin and have important… Expand Platelet-derived growth factor (PDGF)-BB is a well-known smooth muscle (SM) cell (SMC) phenotypic modulator that signals by… Expand BACKGROUND
Platelet-derived growth factor (PDGF) is a central mediator of mesangioproliferative glomerulonephritis (GN). In… Expand The term 'platelet-derived growth factor' (PDGF) refers to a family of disulphide-bonded dimeric isoforms that are important for… Expand The term 'platelet-derived growth factor' (PDGF) refers to a family of disulphide-bonded dimeric isoforms that are important for… Expand