PDE4C gene

Known as: PDE4C, PHOSPHODIESTERASE 4C, cAMP-SPECIFIC, phosphodiesterase E1 dunce homolog (Drosophila) 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2018
024619952018

Papers overview

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Highly Cited
2013
Highly Cited
2013
Human aging is associated with DNA methylation changes at specific sites in the genome. These epigenetic modifications may be… (More)
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2012
2012
Systemic lupus erythematosus is a polymorphic and multigenic inflammatory autoimmune disease. Cyclic AMP (cAMP) modulates… (More)
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2011
2011
Chronic inflammation is a hallmark of pulmonary diseases, which leads to lung parenchyma destruction (emphysema) and obstructive… (More)
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Highly Cited
2005
Highly Cited
2005
Cyclic nucleotide PDE4 (phosphodiesterase 4) inhibitors are being developed as potent anti-inflammatory drugs for use in chronic… (More)
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2005
2005
Cyclic adenosine monophosphate (cAMP) is an important second messenger in the hormonal regulation of bone metabolism. cAMP is… (More)
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2004
2004
Monocytes and macrophages provide key targets for the action of novel anti-inflammatory therapeutics targeted at inhibition of… (More)
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2001
2001
Pre-clinical and clinical studies are currently underway to evaluate the potential of phosphodiesterase-4 (PDE4) inhibitors for… (More)
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2001
2001
PURPOSE Knowledge of intracellular signal propagation in smooth muscle tone regulation is of major importance in the… (More)
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Highly Cited
2000
Highly Cited
2000
We have examined the distribution of four different cyclic AMP-specific phosphodiesterase isozyme (PDE4A, PDE4B, PDE4C and PDE4D… (More)
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1995
1995
Previous studies with U937 cells, a human monocyte cell line, have shown that the activity of cyclic nucleotide phosphodiesterase… (More)
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