PDE4A gene

Known as: PHOSPHODIESTERASE 4A, cAMP-SPECIFIC, PDE4A, DUNCE-LIKE PHOSPHODIESTERASE E2, FORMERLY 
 
National Institutes of Health

Papers overview

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2008
2008
PURPOSE As favorable outcomes from malignant brain tumors remain limited by poor survival and treatment-related toxicity, novel… (More)
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Highly Cited
2007
Highly Cited
2007
Osteoarthritis (OA) is characterized by alterations to subchondral bone as well as articular cartilage. Changes to bone in OA… (More)
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2007
2007
Type 4 phosphodiesterases (PDE4) are critical regulators in TCR signaling by attenuating the negative constraint of cAMP. In this… (More)
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Highly Cited
2003
Highly Cited
2003
Inducible nitric oxide synthase (iNOS) is expressed in both the fibrotic plaque of Peyronie's disease (PD) in the human, and in… (More)
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1999
1999
1. Of the four major phosphodiesterase 4 (PDE4) subtypes, PDE4A, PDE4B and PDE4D are widely expressed in human inflammatory cells… (More)
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Highly Cited
1999
Highly Cited
1999
The WD-repeat protein receptor for activated C-kinase (RACK1) was identified by its interaction with the cyclic AMP-specific… (More)
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1999
1999
The cAMP-specific phosphodiesterase (PDE) HSPDE 4A4B(pde46) selectively bound SH3 domains of SRC family tyrosyl kinases. Such an… (More)
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Highly Cited
1999
Highly Cited
1999
Four cyclic AMP-specific, rolipram-inhibited phosphodiesterases (PDE4s) have been identified in mammals; all four are homologs of… (More)
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1997
1997
The cAMP phosphodiesterase (PDE) 3 and PDE4 isoforms provide the major cAMP-hydrolysing PDE activities in Jurkat T-cells, with… (More)
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1996
1996
The PDE4A (type IV) cAMP-specific, rolipram-inhibited phosphodiesterase RPDE-6 (RNPDE4A5), when transiently expressed in COS7… (More)
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