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PDE2A gene

Known as: PDE2A, Phosphodiesterase 2A, cGMP-Stimulated Gene, PHOSPHODIESTERASE 2A, cGMP-STIMULATED 
This gene is involved in second messenger molecule metabolism.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
3',5'-cyclic nucleotide phosphodiesterases (PDEs) are the only known enzymes to compartmentalize cAMP and cGMP, yet little is… Expand
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Highly Cited
2013
Highly Cited
2013
Although hydrogen sulfide (H₂S) is generally known as a mitochondrial poison, recent studies show that lower concentrations of H… Expand
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Highly Cited
2012
Highly Cited
2012
Rheumatoid arthritis is a common autoimmune disease characterized by chronic inflammation. We report a meta-analysis of genome… Expand
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Highly Cited
2011
Highly Cited
2011
Mitochondria are central organelles in cellular energy metabolism, apoptosis, and aging processes. A signaling network regulating… Expand
Highly Cited
2010
Highly Cited
2010
Phosphodiesterase type 5A (PDE5A) inhibitors acutely suppress beta-adrenergic receptor (β-AR) stimulation in left ventricular… Expand
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Highly Cited
2009
Highly Cited
2009
Phosphodiesterases (PDEs) comprise a family of enzymes that regulate the levels of cyclic nucleotides, key second messengers that… Expand
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Highly Cited
2009
Highly Cited
2009
We report the X-ray crystal structure of a phosphodiesterase (PDE) that includes both catalytic and regulatory domains. PDE2A… Expand
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Review
2009
Review
2009
GAF domains regulate the catalytic activity of certain vertebrate cyclic nucleotide phosphodiesterases (PDEs) by allosteric… Expand
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Highly Cited
2007
Highly Cited
2007
Endothelial barrier dysfunction leading to increased permeability and vascular leakage is an underlying cause of several… Expand
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Highly Cited
2004
Highly Cited
2004
The cytokines macrophage colony-stimulating factor (M-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF) promote… Expand