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PD 150606

Known as: PD-150606, PD150606 
National Institutes of Health

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1 relation

Broader (1)

Acrylates

Papers overview

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2010
2010
Role of calpain-9 and PKC-delta in the apoptotic mechanism of lumen formation in CEACAM1 transfected breast epithelial cells.
Highly Cited
2008
Highly Cited
2008
Calpain‐mediated pathway dominates cisplatin‐induced apoptosis in human lung adenocarcinoma cells as determined by real‐time single cell analysis
Cisplatin is an efficient anticancer agent. Cisplatin‐based chemotherapy is believed to involve different signal transduction… 
2008
2008
Regulation of Calpain Activity by c-Myc through Calpastatin and Promotion of Transformation in c-Myc-negative Cells by Calpastatin Suppression*
The c-Myc transcription factor is commonly dysregulated in cancer. c-Myc also sensitizes cells to apoptosis induced by a variety… 
2007
2007
Specific blockage of ligand-induced degradation of the Ah receptor by proteasome but not calpain inhibitors in cell culture lines from different species.
2005
2005
Inhibition of the cdk5/MEF2 pathway is involved in the antiapoptotic properties of calpain inhibitors in cerebellar neurons
1 Experimental data implicate calpain activation in the pathways involved in neuronal apoptosis. Indeed, calpain inhibitors… 
2005
2005
GLUT4 expression in 3T3-L1 adipocytes is repressed by proteasome inhibition, but not by inhibition of calpains
2004
2004
Ischemia-induced increase in long-term potentiation is warded off by specific calpain inhibitor PD150606
2004
2004
Protection of Mature Oligodendrocytes by Inhibitors of Caspases and Calpains
Mature mouse oligodendrocytes (OLs) are susceptible to death in demyelinating diseases such as multiple sclerosis and in brain… 
2003
2003
Apoptosis induced by simvastatin in rat vascular smooth muscle cell through Ca2+-calpain and caspase-3 dependent pathway.
Highly Cited
2002
Highly Cited
2002
An α-mercaptoacrylic acid derivative (PD150606) inhibits selective motor neuron death via inhibition of kainate-induced Ca2+ influx and not via calpain inhibition
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