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PD 142893

Known as: PD-142893 
National Institutes of Health

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1 relation

Broader (1)

Oligopeptides

Papers overview

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2018
2018
Organ-specific changes in vascular reactivity and roles of inducible nitric oxide synthase and endothelin-1 in a rabbit endotoxic shock model
BACKGROUND Hemorrhagic shock-induced changes in vascular reactivity appear organ-specific. In the present study, we examined the… 
2007
2007
Selektive Blockade des Endothelin-B-Rezeptors verbessert durch gesteigerte arterioläre Perfusion das überleben von kritisch durchbluteten muskulokutanen Lappen
Background: The insufficient perfusion of distal flap areas, which may lead to partial necrosis, still represents a major… 
2004
2004
Characterization of the potent combined endothelin(A/B)-antagonist PD 142893 on cerebral vessels
Abstract A disturbed balance between endothelin (ET)-1 and nitric oxide (NO) seems to play a key role in the development of… 
1998
1998
PD 142893, SB 209670, and BQ 788 selectively antagonize vascular endothelial versus vascular smooth muscle ET(B)-receptor activity in the rat.
The purpose of this study was to determine whether vascular endothelial and vascular smooth-muscle endothelin ET(B) receptors… 
1998
1998
Toward the rational development of peptidomimetic analogs of the C-terminal endothelin hexapeptide: development of a theoretical model.
1998
1998
Atypical receptors mediate the response to endothelin-1 and sarafotoxin S6b in the human umbilical artery.
Highly Cited
1997
Highly Cited
1997
Interaction of nitric oxide and endothelin-1 in ischemia/reperfusion injury of rat heart.
Although several studies have demonstrated that nitric oxide appears to be cardioprotective and endothelin-1 (ET-1) deleterious… 
1997
1997
Endothelin-1 Does not Contribute to Ischemia/Reperfusion-Induced Vasoconstriction in Skeletal Muscle
The experiment reported was designed to investigate whether endothelin-1 (ET-1) contributes to vasospasm and poor perfusion… 
1996
1996
Endothelin receptor synthetic N-terminal fragment interacts with the receptor itself
Highly Cited
1993
Highly Cited
1993
In vitro and in vivo studies with a series of hexapeptide endothelin antagonists.
The effects of different amino acids incorporated into the 16 and 17 positions of the C-terminal hexapeptide of ET-1 were… 
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