PAX8 gene

Known as: PAIRED DOMAIN GENE 8, PAIRED BOX GENE 8, paired box 8 
This gene is involved in thyroid development and transcriptional regulation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2017
0102019902017

Papers overview

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2013
2013
Nephrons comprise a blood filter and an epithelial tubule that is subdivided into proximal and distal segments, but what directs… (More)
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2007
2007
OBJECTIVE Mutations in NKX2.1, NKX2.5, FOXE1 and PAX8 genes, encoding for transcription factors involved in the development of… (More)
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Highly Cited
2006
Highly Cited
2006
A subset of follicular thyroid carcinomas contains a balanced translocation, t(2;3)(q13;p25), that results in fusion of the… (More)
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2006
2006
Follicular thyroid carcinomas are associated with a chromosomal translocation that fuses the thyroid-specific transcription… (More)
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2005
2005
Mutations in the paired domain transcription factor PAX8 are a rare cause of congenital hypothyroidism due to thyroid dysgenesis… (More)
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2005
2005
Vertebrate Pax2 and Pax8 proteins are closely related transcription factors hypothesized to regulate early aspects of inner ear… (More)
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2004
2004
Thyroid dysgenesis is the most common cause of congenital hypothyroidism, a relatively frequent disease affecting 1 in 3000-4000… (More)
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2002
Highly Cited
2002
Recently, a translocation t(2;3)(q13;p25), leading to the formation of a chimeric PAX8-peroxisome proliferator-activated receptor… (More)
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2001
2001
Congenital hypothyroidism associated with thyroid hypoplasia can be caused by several genetic defects, including mutations in the… (More)
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1995
1995
Wilms' tumor (WT) is a childhood renal neoplasm with histological features resembling fetal kidney development. Two members of… (More)
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