PARN, 1-BP INS, 563T

 
National Institutes of Health

Papers overview

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2017
2017
A feedback mechanism between PLD and deadenylase PARN for the shortening of eukaryotic poly(A) mRNA tails that is deregulated in cancer cells
The removal of mRNA transcript poly(A) tails by 3'→5' exonucleases is the rate-limiting step in mRNA decay in eukaryotes. Known… (More)
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2015
2015
PARN deadenylase is involved in miRNA-dependent degradation of TP53 mRNA in mammalian cells
mRNA deadenylation is under the control of cis-acting regulatory elements, which include AU-rich elements (AREs) and microRNA… (More)
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