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PARN, 1-BP INS, 563T

National Institutes of Health

Papers overview

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2016
2016
A feedback mechanism between PLD and deadenylase PARN for the shortening of eukaryotic poly(A) mRNA tails that is deregulated in cancer cells
ABSTRACT The removal of mRNA transcript poly(A) tails by 3′→5′ exonucleases is the rate-limiting step in mRNA decay in eukaryotes… 
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