PARK7 protein, human

Known as: Parkinson disease (autosomal recessive, early onset) 7, human, DJ1 protein, human, Protein DJ-1 
Protein DJ-1 (189 aa, ~20 kDa) is encoded by the human PARK7 gene. This protein plays a role in the downregulation of apoptosis.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2017
02420042017

Papers overview

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2017
2017
Methylglyoxal (MG) is a reactive metabolite that forms adducts on cysteine, lysine and arginine residues of proteins, thereby… (More)
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2017
2017
DJ-1 mutations are associated to early-onset Parkinson's disease and accounts for about 1-2% of the genetic forms. The protein is… (More)
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2016
2016
AIMS Hypoxic-ischemia alters mitochondrial membrane potential (Δψm), respiratory-related enzymes, and mitochondrial DNA (mtDNA… (More)
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2015
2015
The aim of our study was to assess the differential gene expression of Parkinson protein 7 (PARK7) interactome in malignant… (More)
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2014
2014
The molecular mechanisms underlying skeletal muscle aging and associated sarcopenia have been linked to an altered oxidative… (More)
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2011
2011
DJ-1 (PARK7) is a neuroprotective protein that protects cells from oxidative stress. Accordingly, loss-of-function DJ-1 mutations… (More)
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2011
2011
DJ-1, Parkinson's disease PARK7, acts as an oxidative stress sensor in neural cells. Recently, we identified the DJ-1 modulator… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Mitochondrial dysfunction and degradation takes a central role in current paradigms of neurodegeneration in Parkinson… (More)
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2010
2010
Warfarin is a commonly prescribed oral anti-coagulant with narrow therapeutic index. It interferes with vitamin K cycle to… (More)
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2008
2008
Ad.mda-7 inhibited growth and decreased survival in a broad array of human tumor cells, without eliciting detrimental effects in… (More)
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