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PARD3 gene

Known as: PPP1R118, protein phosphatase 1, regulatory subunit 118, Par-3 Family Cell Polarity Regulator Gene 
This gene is involved in asymmetric cell division, signal transduction, and tight junction formation.
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Cell polarity is critical for epithelial structure and function. Adherens junctions (AJs) often direct this polarity, but we… Expand
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Highly Cited
2004
Highly Cited
2004
During convergent extension in Drosophila, polarized cell movements cause the germband to narrow along the dorsal-ventral (D-V… Expand
Highly Cited
2003
Highly Cited
2003
Several protein complexes that are involved in epithelial apicobasal polarity have been identified. However, the mechanism by… Expand
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Highly Cited
2003
Highly Cited
2003
Polarized cells contain numerous membrane domains, but it is unclear how the formation of these domains is coordinated to create… Expand
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Highly Cited
2000
Highly Cited
2000
Asymmetric localization is a prerequisite for inscuteable (insc) to function in coordinating and mediating asymmetric cell… Expand
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Highly Cited
2000
Highly Cited
2000
The establishment and maintenance of polarity is of fundamental importance for the function of epithelial and neuronal cells. In… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND In the fruit fly Drosophila, the Inscuteable protein localises to the apical cell cortex in neuroblasts and directs… Expand
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Highly Cited
1999
Highly Cited
1999
Asymmetric cell divisions can be generated by the segregation of determinants into one of the two daughter cells. In Drosophila… Expand
Highly Cited
1999
Highly Cited
1999
Asymmetric cell division generates daughter cells with different developmental fates from progenitor cells that contain localized… Expand
Highly Cited
1996
Highly Cited
1996
Cellularization of the Drosophila embryo results in the formation of a cell monolayer with many characteristics of a polarized… Expand
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