PARD3 gene

Known as: PPP1R118, protein phosphatase 1, regulatory subunit 118, Par-3 Family Cell Polarity Regulator Gene 
This gene is involved in asymmetric cell division, signal transduction, and tight junction formation.

Topic mentions per year

Topic mentions per year

1970-2017
0102019702017

Papers overview

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Highly Cited
2006
Highly Cited
2006
BACKGROUND In a specialized epithelial cell such as the Drosophila photoreceptor, a conserved set of proteins is essential for… (More)
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Highly Cited
2004
Highly Cited
2004
During convergent extension in Drosophila, polarized cell movements cause the germband to narrow along the dorsal-ventral (D-V… (More)
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Highly Cited
2003
Highly Cited
2003
Polarized cells contain numerous membrane domains, but it is unclear how the formation of these domains is coordinated to create… (More)
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Highly Cited
2003
Highly Cited
2003
Several protein complexes that are involved in epithelial apicobasal polarity have been identified. However, the mechanism by… (More)
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Highly Cited
2003
Highly Cited
2003
PAR-1 kinases are required for polarity in diverse cell types, such as epithelial cells, where they localize laterally. PAR-1… (More)
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Highly Cited
2000
Highly Cited
2000
The establishment and maintenance of polarity is of fundamental importance for the function of epithelial and neuronal cells. In… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND In the fruit fly Drosophila, the Inscuteable protein localises to the apical cell cortex in neuroblasts and directs… (More)
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Highly Cited
2000
Highly Cited
2000
The Drosophila protein Bazooka is required for both apical–basal polarity in epithelial cells and directing asymmetric cell… (More)
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Highly Cited
1999
Highly Cited
1999
Asymmetric cell division generates daughter cells with different developmental fates from progenitor cells that contain localized… (More)
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Highly Cited
1999
Highly Cited
1999
Asymmetric cell divisions can be generated by the segregation of determinants into one of the two daughter cells. In Drosophila… (More)
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