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PAR-1-activating peptide

Known as: PAR-1-AP, TFLLR-NH2, threonyl-phenylalanyl-leucyl-leucyl-argininamide 
 
National Institutes of Health

Papers overview

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2012
2012
BACKGROUND AND PURPOSE Increased vascular contractility plays a fundamental role in cerebral vasospasm in subarachnoid… Expand
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Highly Cited
2011
Highly Cited
2011
The present study characterized platelet secretion and surface expression of proangiogenic stromal cell-derived factor-1α (SDF-1… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Platelets release the immune-modulating lipid sphingosine-1-phosphate (S1P). However, the mechanisms of platelet S1P… Expand
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2008
2008
INTRODUCTION A polymorphism (-14 A/T) affecting PAR1 expression on the platelet surface has recently been identified. A two-fold… Expand
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2007
2007
Pathological conditions such as coronary artery disease are clinically controlled via therapeutic regulation of platelet activity… Expand
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2004
2004
Thrombin and related protease-activated receptors 1, 2, 3, and 4 (PAR1-4) play a multifunctional role in many types of cells… Expand
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2003
2003
Thrombin-induced platelet activation involves cleavage of protease-activated receptors (PARs) 1 and 4, and interaction, via… Expand
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Highly Cited
2002
Highly Cited
2002
Protease-activated receptors (PARs), newly identified members of G protein-coupled receptors, are widely distributed in the brain… Expand
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2002
2002
Proteinase-activated receptor-1 (PAR-1) is activated by thrombin and can be selectively activated by synthetic peptides (PAR-1… Expand
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2001
2001
Thrombin (THR) plays a key role in the brain under physiological and pathological conditions. Several of the biological… Expand
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