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PAK1 protein, human

Known as: EC 2.7.1.3, p21-Activated Kinase 1, p21-Cdc42-Rac1-activated kinase 1 (STE20 homolog, yeast) protein, human 
Serine/threonine-protein kinase PAK 1 (545 aa, ~61 kDa) is encoded by the human PAK1 gene. This protein is involved in both protein phosphorylation… Expand
National Institutes of Health

Papers overview

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2015
2015
Acetylcholine receptor (AChR) expression in innervated muscle is limited to the synaptic region. Neuron-induced electrical… Expand
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Highly Cited
2008
Highly Cited
2008
MicroRNAs are noncoding RNAs that inhibit the expression of their targets in a sequence-specific manner and play crucial roles… Expand
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2007
2007
The serine/threonine kinase p21-activated kinase 1 (Pak1) modulates actin and microtubule dynamics. The neuronal functions of… Expand
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2007
2007
p21-activated kinase 1 (PAK1) is a mediator of downstream signaling from the small GTPases Rac and Cdc42. In its inactive state… Expand
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Highly Cited
2004
Highly Cited
2004
GEF-H1 is a guanine nucleotide exchange factor for Rho whose activity is regulated through a cycle of microtubule binding and… Expand
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Highly Cited
2003
Highly Cited
2003
A variety of intracellular signaling pathways are linked to cell surface receptor signaling through their recruitment by Src… Expand
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Highly Cited
2002
Highly Cited
2002
The serine/threonine kinase p21-activated kinase 1 (Pak1) controls the actin cytoskeletal and ruffle formation through mechanisms… Expand
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Highly Cited
2000
Highly Cited
2000
In this study, we show that phosphorylated 3-phosphoinositide-dependent kinase 1 (PDK1) phosphorylates p21-activated kinase 1… Expand
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Highly Cited
1999
Highly Cited
1999
Leukocyte chemoattractants are known to stimulate signaling pathways that involve Rho family GTPases. Direct evidence for the… Expand
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Highly Cited
1998
Highly Cited
1998
Rho-family GTPases regulate cytoskeletal dynamics in various cell types. p21-activated kinase 1 (PAK1) is one of the downstream… Expand
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