PAFAH1B1 gene

Known as: LIS1 GENE, PAFAH1B1, LIS1 
This gene is involved in the modulation of neuronal migration.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2017
010203019822017

Papers overview

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Highly Cited
2010
Highly Cited
2010
Cytoplasmic dynein is responsible for many aspects of cellular and subcellular movement. LIS1, NudE, and NudEL are dynein… (More)
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Highly Cited
2009
Highly Cited
2009
Nuclear movement is critical during neurogenesis and neuronal migration, which are fundamental for mammalian brain development… (More)
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Highly Cited
2008
Highly Cited
2008
A strong candidate gene for schizophrenia and major mental disorders, disrupted-in-schizophrenia 1 (DISC1) was first described in… (More)
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Highly Cited
2005
Highly Cited
2005
Mutations in the human LIS1 gene cause the smooth brain disease classical lissencephaly. To understand the underlying mechanisms… (More)
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Highly Cited
2004
Highly Cited
2004
Humans with mutations in either DCX or LIS1 display nearly identical neuronal migration defects, known as lissencephaly. To… (More)
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Highly Cited
2003
Highly Cited
2003
Loss-of-function mutations in RELN (encoding reelin) or PAFAH1B1 (encoding LIS1) cause lissencephaly, a human neuronal migration… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND During anaphase in budding yeast, dynein inserts the mitotic spindle across the neck between mother and daughter cells… (More)
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Highly Cited
1998
Highly Cited
1998
Heterozygous mutation or deletion of the ß subunit of platelet-activating factor acetylhydrolase (PAFAH1B1, also known as LIS1… (More)
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Highly Cited
1995
Highly Cited
1995
During a study of the genetics of nuclear migration in the filamentous fungus Aspergillus nidulans, we cloned a gene, nudF, which… (More)
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Highly Cited
1993
Highly Cited
1993
Lissencephaly (agyria-pachygyria) is a human brain malformation manifested by a smooth cerebral surface and abnormal neuronal… (More)
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