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PAFAH1B1 gene

Known as: LIS1 GENE, PAFAH1B1, LIS1 
This gene is involved in the modulation of neuronal migration.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
A strong candidate gene for schizophrenia and major mental disorders, disrupted-in-schizophrenia 1 (DISC1) was first described in… Expand
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Highly Cited
2005
Highly Cited
2005
Mutations in the human LIS1 gene cause the smooth brain disease classical lissencephaly. To understand the underlying mechanisms… Expand
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Highly Cited
2004
Highly Cited
2004
Correct neuronal migration and positioning during cortical development are essential for proper brain function. Mutations of the… Expand
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Highly Cited
2000
Highly Cited
2000
Whereas total loss of Lis1 is lethal, disruption of one allele of the Lis1 gene results in brain abnormalities, indicating that… Expand
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Highly Cited
2000
Highly Cited
2000
Mutations in the LIS1 gene cause gross histological disorganization of the developing human brain, resulting in a brain surface… Expand
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Highly Cited
2000
Highly Cited
2000
Mutations in mammalian Lis1 (Pafah1b1) result in neuronal migration defects. Several lines of evidence suggest that LIS1… Expand
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Highly Cited
2000
Highly Cited
2000
Disruption of one allele of the LIS1 gene causes a severe developmental brain abnormality, type I lissencephaly. In Aspergillus… Expand
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Highly Cited
1998
Highly Cited
1998
Heterozygous mutation or deletion of the ß subunit of platelet-activating factor acetylhydrolase (PAFAH1B1, also known as LIS1… Expand
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Highly Cited
1993
Highly Cited
1993
Lissencephaly (agyria-pachygyria) is a human brain malformation manifested by a smooth cerebral surface and abnormal neuronal… Expand
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Highly Cited
1993
Highly Cited
1993
LISSENCEPHALY (agyria-pachygyria) is a human brain malformation manifested by a smooth cerebral surface and abnormal neuronal… Expand
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