PA 824

Known as: PA-824, PA824 cpd 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2018
05101520002018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
BACKGROUND New drugs, but also shorter, better-tolerated regimens are needed to tackle the high global burden of tuberculosis… (More)
  • table 1
  • table 2
  • table 3
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2011
Highly Cited
2011
To truly transform the landscape of tuberculosis treatment, novel regimens containing at least 2 new drugs are needed to simplify… (More)
  • table 1
  • table 2
  • figure 1
  • figure 4
  • figure 2
Is this relevant?
Highly Cited
2010
Highly Cited
2010
PA-824 is a novel nitroimidazo-oxazine being evaluated for its potential to improve tuberculosis (TB) therapy. This randomized… (More)
  • figure 1
  • table 1
  • table 2
  • table 3
  • figure 3
Is this relevant?
2009
2009
PA-824 is a novel antibacterial agent that has shown in vitro activity against both drug-sensitive and drug-resistant… (More)
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Bicyclic nitroimidazoles, including PA-824, are exciting candidates for the treatment of tuberculosis. These prodrugs require… (More)
  • figure 2
  • figure 1
  • figure 3
Is this relevant?
Highly Cited
2008
Highly Cited
2008
PA-824 is a nitroimidazo-oxazine in clinical testing for the treatment of tuberculosis. We report that the novel combination of… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
PA-824 is a promising new compound for the treatment of tuberculosis that is currently undergoing human trials. Like its… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 4
  • figure 3
Is this relevant?
2006
2006
Leprosy responds very slowly to the current multidrug therapy, and hence there is a need for novel drugs with potent bactericidal… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
The nitroimidazopyran PA-824 has potent in vitro activity against Mycobacterium tuberculosis, a narrow spectrum of activity… (More)
  • table 2
  • table 1
  • figure 1
  • table 3
  • figure 2
Is this relevant?
Highly Cited
2005
Highly Cited
2005
This study extends earlier reports regarding the in vitro and in vivo efficacies of the nitroimidazopyran PA-824 against… (More)
Is this relevant?