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P-glycoprotein 2

Known as: MDR2 protein, Multidrug resistance protein 2, pgp2 protein 
 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Many drugs prescribed to children are drug transporter substrates. Drug transporters are membrane-bound proteins that mediate the… Expand
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Highly Cited
2004
Highly Cited
2004
The function of hepatic transporters is to move organic substances across sinusoidal and canalicular membranes. During… Expand
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Highly Cited
2003
Highly Cited
2003
Multidrug resistance protein 2 (MRP2) belongs to the ATP binding cassette family of transporters. Its substrates include organic… Expand
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Highly Cited
2001
Highly Cited
2001
The ATP-binding cassette (ABC) proteins comprise a large superfamily of transmembrane transporters that utilize the energy of ATP… Expand
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Highly Cited
2001
Highly Cited
2001
Dubin-Johnson syndrome (DJS) is an inherited disorder characterized by conjugated hyperbilirubinemia and is caused by a… Expand
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Highly Cited
2000
Highly Cited
2000
The multidrug resistance proteins MRP2 (symbol ABCC2) and MRP3 (symbol ABCC3) are conjugate export pumps expressed in hepatocytes… Expand
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Highly Cited
2000
Highly Cited
2000
We have studied regulation of the multidrug resistance protein 2 (mrp2) during bile duct ligation (BDL) in the rat. In… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND & AIMS Progressive familial intrahepatic cholestasis (PFIC), an inherited liver disease of childhood, is characterized… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND & AIMS Endotoxin lipopolysaccharide (LPS) induces cholestasis and down-regulates the multidrug resistance protein 2… Expand
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Review
1997
Review
1997
The liver converts endogenous and xenobiotic lipophilic compounds into anionic conjugates with glutathione, glucuronate, or… Expand
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