P-TEFb complex

Known as: P-TEFb complex location 
A dimeric positive transcription elongation factor complex b that comprises a cyclin-dependent kinase containing the catalytic subunit, Cdk9, and a… (More)
National Institutes of Health

Papers overview

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Review
2008
Review
2008
P-TEFb (CycT1:Cdk9), the metazoan RNA polymerase II Ser2 C-terminal domain (CTD) kinase, regulates transcription elongation at… (More)
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Highly Cited
2007
Highly Cited
2007
We have identified a conserved region in the C-terminal domain of bromodomain-containing protein 4 (BRD4) that mediates its… (More)
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Highly Cited
2005
Highly Cited
2005
Brd4 is a mammalian bromodomain protein that binds to acetylated chromatin. Proteomic analysis revealed that Brd4 interacts with… (More)
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Highly Cited
2005
Highly Cited
2005
The cyclinT1/Cdk9 heterodimer that constitutes core P-TEFb is generally presumed to be the transcriptionally active form for… (More)
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Highly Cited
2004
Highly Cited
2004
Positive transcription elongation factor b (P-TEFb) is a kinase that phosphorylates the carboxyl-terminal domain (CTD) of RNA… (More)
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Highly Cited
2001
Highly Cited
2001
To stimulate transcriptional elongation of HIV-1 genes, the transactivator Tat recruits the positive transcription elongation… (More)
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Highly Cited
1998
Highly Cited
1998
Tat stimulates human immunodeficiency virus type 1 (HIV-1) transcription elongation through recognition of the transactivation… (More)
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Highly Cited
1997
Highly Cited
1997
P-TEFb is a key regulator of the process controlling the processivity of RNA polymerase II and possesses a kinase activity that… (More)
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Highly Cited
1997
Highly Cited
1997
To identify novel inhibitors of transcriptional activation by the HIV Tat protein, we used a combination of in vitro and in vivo… (More)
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Highly Cited
1995
Highly Cited
1995
Production of full-length runoff transcripts in vitro and functional mRNA in vivo is sensitive to the drug 5,6-dichloro-1-beta-D… (More)
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