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P 7521

Known as: P-7521 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Bridged Bicyclo Compounds, Heterocyclic

Papers overview

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1990
1990
A potent and long-lasting ligand, azabicyclononane (P-7521).
1990
1990
A potent and long-lasting ligand, azabicyclononane (P-7521).
1989
1989
P-7521--a new irreversible opioid ligand.
In the receptor binding assay, P-7521 was a potent opioid ligand which acted mainly on mu receptor. The relative affinity ratio… 
1988
1988
[Effects of the long-acting analgesics 3-(beta-phenylethyl)-9 beta-methoxy-9 alpha-(m-hydroxyphenyl)-3-azabicycles [3,3,1]-nonane (P-7521) on opiate receptor binding in vitro].
After 6 washes, rat brain P2 membranes preincubated with P-7521 showed only a 15% recovery of [3H]etorphine binding activity… 
1987
1987
[Analgesic activity and respiratory inhibition of 3-beta-phenylethyl)-9 beta-methoxy-9 alpha-(m-hydroxyphenyl)-3-azabicyclo [3,3,1]-nonane (P-7521) in rabbits].
P-7521 is an azabicycloalkane derivative. When P-7521 was given iv to rabbits, its analgesic ED50 was 0.37μg/kg, the analgesic… 
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