Oseltamivir phosphate

The phosphate salt of oseltamivir, a synthetic derivative prodrug of ethyl ester with antiviral activity. By blocking neuraminidases on the surfaces… (More)
National Institutes of Health

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2014
2014
BACKGROUND Resistance to drug therapy, along with high rates of metastasis, contributes to the low survival rate in patients… (More)
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2012
2012
Oseltamivir is an antiviral drug, a neuraminidase inhibitor used in the treatment and prophylaxsis of both influenza A and… (More)
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Highly Cited
2010
Highly Cited
2010
To the Editor: Oseltamivir-resistant infection with the 2009 pandemic influenza A (H1N1) virus has so far been described only… (More)
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Review
2010
Review
2010
Influenza is a transmissible viral pathogen that continues to cause substantial morbidity and mortality. Oseltamivir is an orally… (More)
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2009
2009
The effects of loading doses and probenecid coadministration on oseltamivir pharmacokinetics at four increasing dose levels in… (More)
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2009
2009
BACKGROUND Oseltamivir phosphate (OP; Tamiflu) is a prodrug of the anti-influenza neuraminidase inhibitor oseltamivir carboxylate… (More)
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Highly Cited
2009
Highly Cited
2009
Two neuraminidase (NA) inhibitors, zanamivir (Relenza) and oseltamivir phosphate (Tamiflu), have been licensed for the treatment… (More)
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Review
2007
Review
2007
Oseltamivir phosphate is a prodrug of oseltamivir carboxylate, a highly specific inhibitor of influenza virus neuraminidases… (More)
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Highly Cited
2000
Highly Cited
2000
CONTEXT Previous studies have shown oseltamivir, a neuraminidase inhibitor, to be effective in preventing influenza and treating… (More)
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2000
2000
In 1997, an H5N1 avian influenza A/Hong Kong/156/97 virus transmitted directly to humans and killed six of the 18 people infected… (More)
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