Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Orphenadrine

Known as: ?-dimethylaminoethyl 2-methylbenzhydryl ether, 2-(phenyl-o-tolylmethoxy)ethyldimethylamine, Phenyl-O-tolylmethyl dimethyaminoethyl ether 
A muscarinic antagonist with muscle relaxant activity. Although the mechanism of action has not been determined, orphenadrine appears to block… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
The subthalamic nucleus (STN) has a key role in the pathophysiology of Parkinson's disease and is the primary target for high… Expand
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Despite several studies and models, much remains unclear about how the human basal ganglia operate. Deep brain stimulation (DBS… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Ketamine is a widely used drug for its anesthetic and analgesic properties; it is also considered as a drug of abuse, as many… Expand
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Background Drug eruptions are among the most common cutaneous disorders encountered by the dermatologist. Some drug eruptions… Expand
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Nine organic solvents and 47 commonly used P450 substrates and inhibitors were examined for their effects on coumarin 7… Expand
Is this relevant?
Highly Cited
1997
Highly Cited
1997
The specificities of orphenadrine and methimazole on eight human liver P450 enzyme activities were evaluated by studying the… Expand
  • table 1
  • figure 3
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
1993
Highly Cited
1993
The present study identifies the specific human cytochrome P-450 (CYP) enzymes involved in hydroxylation leading to activation of… Expand
  • table 20
  • figure 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
1990
Highly Cited
1990
Several studies support the hypothesis of 5-HT (serotonin) involvement in the physiopathology of the extrapyramidal system… Expand
Is this relevant?
Highly Cited
1987
Highly Cited
1987
&NA; The formalin test in mice is a valid and reliable model of nociception and is sensitive for various classes of analgesic… Expand
Is this relevant?
Highly Cited
1975
Highly Cited
1975
1 Two studies were carried out on acutely psychotic patients receiving chlorpromazine (100 mg) 8-hourly. 2 In the pilot study on… Expand
Is this relevant?