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Ornithine carbamoyltransferase deficiency

Known as: Deficiency, OTC, Deficiencies, OTC, octd 
An inherited urea cycle disorder associated with deficiency of the enzyme ORNITHINE CARBAMOYLTRANSFERASE, transmitted as an X-linked trait and… 
National Institutes of Health

Related topics

Related topics

25 relations
Alkalosis, RespiratoryAmino acidemia disorder suspected:Prid:Pt:Bld.dot:NomCerebral EdemaComatose

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1986
1986
Restoration of the polyamine contents in rat hepatoma tissue-culture cells after inhibition of polyamine biosynthesis. Relationship with cell proliferation.
The restoration of the polyamine content in polyamine-deficient rat hepatoma tissue-culture (HTC) cells, after short duration of… 
1983
1983
Induction of ornithine decarboxylase activity and DNA synthesis in hairless mouse epidermis by retinoids.
The ability of all-trans-retinoic acid (RA) and other retinoid derivatives to enhance DNA synthesis and to induce ornithine… 
1981
1981
A method for the selection of deletion mutations in the L-proline catabolism gene cluster of Aspergillus nidulans.
Interest in the selection of mutations affecting L-proline catabolism in Aspergillus nidulans is heightened by the involvement of… 
Highly Cited
1977
Highly Cited
1977
Vitamin A acid (retinoic acid), a potent inhibitor of 12-O-tetradecanoyl-phorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis.
Summary Topical application of retinoic acid to mouse skin led to a dramatic inhibition of phorbol ester (12- O -tetradecanoyl… 
Highly Cited
1977
Highly Cited
1977
Structure and function of ornithine carbamoyltransferases.
The reaction catalyzed by ornithine carbamoyltransferase can participate in either the anabolism or the catabolism of arginine… 
Highly Cited
1976
Highly Cited
1976
Activation of 3':5'-cyclic AMP-dependent protein kinase and induction of ornithine decarboxylase as early events in induction of mixed-function oxygenases.
The parenteral administration of a single dose of 3-methylcholanthrene to rats caused an increase in the liver of the… 
1975
1975
Potential inhibitors of polyamine biosynthesis. 2. alpha-Alkyl- and benzyl-(+/-)-ornithine.
Alpha-Methyl-(+/-)-ornithine hydrochloride was not a substrate for ornithine decarboxylase from rat prostate glands. It produced… 
1968
1968
Mutants of Neurospora crassa Deficient in Ornithine-δ-Transaminase
The arg-12s mutation of Neurospora causes a partial block in the ornithine transcarbamylase (OTC) reaction. Strains carrying this… 
1964
1964
The kinetics of hydrolysis of derivatives of arginine, homoarginine and ornithine by trypsin.
Trypsin catalyses the hydrolysis of suitable derivatives of basic amino acids including peptides, amides and esters. Esters are… 
Highly Cited
1953
Highly Cited
1953
Ornithine transaminase in Neurospora and its relation to the biosynthesis of proline.
The mould Neurospora crassa is normally able to interconvert proline and ornithine, since either proline or ornithine will… 
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