Ornithine carbamoyltransferase deficiency

Known as: Deficiency, OTC, Deficiencies, OTC, octd 
An inherited urea cycle disorder associated with deficiency of the enzyme ORNITHINE CARBAMOYLTRANSFERASE, transmitted as an X-linked trait and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1947-2018
0204019472017

Papers overview

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2013
2013
Ornithine carbamoyltransferase deficiency is the most common inherited defect of the urea cycle. We examined 28 male and 9 female… (More)
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2012
2012
Ornithine carbamoyltransferase (OTC) deficiency is a urea cycle disorder that causes the accumulation of ammonia, which can lead… (More)
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Highly Cited
2011
Highly Cited
2011
Emerging evidence suggests that protein acetylation is a broad-ranging regulatory mechanism. Here we utilize acetyl-peptide… (More)
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Highly Cited
2003
Highly Cited
2003
We report the death of an 18-year-old male with partial ornithine transcarbamylase (OTC) deficiency who participated in a pilot… (More)
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2002
2002
BACKGROUND Ornithine carbamoyltransferase (OCT) deficiency is the commonest of the inherited urea cycle disorders. AIMS To… (More)
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1991
1991
Ornithine carbamoyltransferase (OCT; EC 2.1.3.3) deficiency, an X-linked disorder (McKusick 31125) presents many forms of onset… (More)
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Highly Cited
1990
Highly Cited
1990
We have investigated the mechanism by which cultured endothelial cells generate L-arginine (L-Arg), the substrate for the… (More)
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1989
1989
A new ornithine carbamoyltransferase variant is described with a nearly normal specific enzymatic activity. This new variant is… (More)
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Highly Cited
1973
Highly Cited
1973
In Aspergillus nidulans, mutations, designated areAr, can result in the inability to utilise a wide variety of nitrogen sources… (More)
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Highly Cited
1956
Highly Cited
1956
Compounds Used-N”l-Acetyl-n-ornithine was synthesized as previously described (5, 3).’ L-Ornithine monohydrochloride was obtained… (More)
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