FAQ

Ornithine Carbamoyltransferase, Mitochondrial, human

Known as: EC 2.1.3.3, Ornithine Transcarbamylase, OTCase 
Ornithine carbamoyltransferase, mitochondrial (354 aa, ~40 kDa) is encoded by the human OTC gene. This protein plays a role in the metabolism of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1967-2017
051019672017

Related topics

Related topics

6 relations
Enzyme GeneHomo sapiensOTC geneTransferase Gene
(More)

Broader (1)

ORNITHINE CARBAMOYLTRANSFERASE

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
Ornithine Carbamoyltransferase, Mitochondrial, human
Homo sapiens
protein metabolism
ORNITHINE CARBAMOYLTRANSFERASE
OTC gene
Enzyme Gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1999
1999
Nitrogen excretion and expression of urea cycle enzymes in the atlantic cod (Gadus morhua l.): a comparison of early life stages with adults
For many years, the urea cycle was considered to be relatively unimportant in the life history of most teleost fishes. In… (More)
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1999
1999
OTC and AUL1, two convergent and overlapping genes in the nuclear genome of Arabidopsis thaliana.
In contrast to bacterial, fungal and vertebrate ornithine transcarbamylases (OTCs; EC 2.1.3.3), very little is known about the… (More)
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1998
1998
The crystal structure of Pyrococcus furiosus ornithine carbamoyltransferase reveals a key role for oligomerization in enzyme stability at extremely high temperatures.
The Pyrococcus furiosus (PF) ornithine carbamoyltransferase (OTCase; EC 2.1.3.3) is an extremely heat-stable enzyme that… (More)
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1996
1996
The urea cycle of Helicobacter pylori.
The presence and activities of the enzymes of the urea cycle in the bacterium Helicobacter pylori were investigated employing one… (More)
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1995
1995
Induction of ornithine-urea cycle enzymes and nitrogen metabolism and excretion in rainbow trout (Oncorhynchus mykiss) during early life stages
The ornithine­urea cycle (OUC) is present in elasmobranch fish and many terrestrial vertebrates. Recently, a functional OUC… (More)
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1989
1989
Scanning detection of mutations in human ornithine transcarbamoylase by chemical mismatch cleavage.
The mutations in X chromosome-linked diseases are frequently heterogeneous, and yet only a small fraction can be detected by… (More)
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1988
1988
Two mitochondrial matrix proteases act sequentially in the processing of mammalian matrix enzymes.
The imported precursors of the mammalian matrix enzymes malate dehydrogenase [(S)-malate:NAD+ oxidoreductase, EC 1.1.1.37] and… (More)
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1988
1988
Distribution of glutamine synthetase and carbamoyl-phosphate synthetase I in vertebrate liver.
Mitochondrial glutamine synthetase (EC 6.3.1.2) is the primary ammonia-detoxifying enzyme in avian liver and is therefore… (More)
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1985
1985
Gene deletion and restriction fragment length polymorphisms at the human ornithine transcarbamylase locus.
Deficiency of ornithine transcarbamylase (OTC; EC 2.1.3.3), a hepatic mitochondrial enzyme involved in the detoxification of… (More)
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1984
1984
Molecular cloning and nucleotide sequence of cDNA for rat ornithine carbamoyltransferase precursor.
Messenger RNA of rat ornithine carbamoyltransferase (EC 2.1.3.3), a mitochondrial matrix enzyme, was enriched by… (More)
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