Oncolytic Viruses

Known as: Oncolytic Virus, Virus, Oncolytic, Viruses, Oncolytic 
A type of virus that infects and lyses (breaks down) cancer cells but not normal cells. Oncolytic viruses can occur naturally or can be made in the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1954-2017
05010019542016

Papers overview

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Review
2015
Review
2015
INTRODUCTION Over the past decade, the cytolytic capabilities of oncolytic viruses (OVs), exploited to selectively eliminate… (More)
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Highly Cited
2010
Highly Cited
2010
A major barrier to all oncolytic viruses (OVs) in clinical development is cellular innate immunity, which is variably active in a… (More)
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Highly Cited
2008
Highly Cited
2008
Replication-conditional (oncolytic) mutants of herpes simplex virus (HSV), are considered promising therapeutic alternatives for… (More)
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Highly Cited
2007
Highly Cited
2007
Previously, we reported that a recombinant vaccinia virus (VACV) carrying a light-emitting fusion gene enters, replicates in, and… (More)
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Highly Cited
2007
Highly Cited
2007
Oncolytic viruses (OVs) are selected or designed to eliminate malignancies by direct infection and lysis of cancer cells. In… (More)
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Highly Cited
2006
Highly Cited
2006
  • Ken Garber
  • Journal of the National Cancer Institute
  • 2006
Oncolytic virus research got a welcome boost last November when Chinese regulators approved the world’s fi rst oncolytic viral… (More)
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Highly Cited
2006
Highly Cited
2006
Natural and genetically modified oncolytic viruses have been systematically tested as anticancer therapeutics. Among this group… (More)
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Highly Cited
2006
Highly Cited
2006
We undertook a Phase I/II trial in patients with apparent recurrent glioblastoma multiforme (GBM) based on imaging studies to… (More)
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Highly Cited
2002
Highly Cited
2002
PURPOSE PV701, a replication-competent strain of Newcastle disease virus, causes regression of tumor xenografts after intravenous… (More)
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Highly Cited
2000
Highly Cited
2000
Interferons are circulating factors that bind to cell surface receptors, activating a signaling cascade, ultimately leading to… (More)
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