Oncogene Protein p21(ras)

Known as: p21(v-Ki-ras), Oncogene Protein p21(ras) [Chemical/Ingredient], p21 v ras 
Transforming protein encoded by ras oncogenes. Point mutations in the cellular ras gene (c-ras) can also result in a mutant p21 protein that can… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2018
0102019822018

Papers overview

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Highly Cited
2004
Highly Cited
2004
The activated Ras oncogene can transform various mammalian cells and has been implicated in development of a high population of… (More)
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1999
1999
The oncogenic ras protein controls signal-transduction pathways that are critical for cell proliferation and tumorigenesis. Here… (More)
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1991
1991
The protein product of the H-ras oncogene, p21, has been measured semiquantitatively in solubilized particulate fractions of 160… (More)
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Highly Cited
1990
Highly Cited
1990
The crystal structure of the H-ras oncogene protein p21 complexed to the slowly hydrolysing GTP analogue GppNp has been… (More)
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Highly Cited
1990
Highly Cited
1990
Identifying the nature of the genetic mutations in thyroid neoplasms and their prevalence in the various tumor phenotypes is… (More)
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Highly Cited
1990
Highly Cited
1990
Polymerase chain reaction (PCR) amplification followed by oligonucleotide probing was used to investigate the presence of ras… (More)
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Highly Cited
1989
Highly Cited
1989
The crystal structure of the guanine-nucleotide-binding domain of p21 (amino acids 1–166) complexed to the guanosine triphosphate… (More)
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1989
1989
The polymerase chain reaction (PCR) technique has greatly facilitated the identification of ras oncogenes by allele-specific… (More)
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Highly Cited
1988
Highly Cited
1988
Using in vitro gene amplification by the polymerase chain reaction (PCR) and mutation detection by the RNAase A mismatch cleavage… (More)
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Highly Cited
1987
Highly Cited
1987
The MCF-7 human breast cancer cell line responds to estrogen stimulation in vitro by increased secretion of growth factors and… (More)
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