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Oncogene Protein p21(ras)

Known as: p21(v-Ki-ras), Oncogene Protein p21(ras) [Chemical/Ingredient], p21 v ras 
Transforming protein encoded by ras oncogenes. Point mutations in the cellular ras gene (c-ras) can also result in a mutant p21 protein that can… Expand
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
The activated Ras oncogene can transform various mammalian cells and has been implicated in development of a high population of… Expand
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Highly Cited
2001
Highly Cited
2001
The reactive cysteines in H-ras are subject to oxidative modifications that potentially alter the cellular function of this… Expand
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Highly Cited
1997
Highly Cited
1997
Conversion of Ras proteins into an activated GTP-bound state able to bind effector proteins is catalyzed by specific guanine… Expand
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Highly Cited
1993
Highly Cited
1993
In order to scrutinize the possible significance of (nonatypical) mucous cell hyperplasia of the pancreas to neoplasia, we… Expand
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Highly Cited
1990
Highly Cited
1990
The crystal structure of the H-ras oncogene protein p21 complexed to the slowly hydrolysing GTP analogue GppNp has been… Expand
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Highly Cited
1990
Highly Cited
1990
The X-ray structures of the guanine nucleotide binding domains (amino acids 1-166) of five mutants of the H-ras oncogene product… Expand
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Highly Cited
1989
Highly Cited
1989
The crystal structure of the guanine-nucleotide-binding domain of p21 (amino acids 1–166) complexed to the guanosine triphosphate… Expand
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Highly Cited
1989
Highly Cited
1989
The strain A mouse has a high incidence of spontaneous lung tumors and is susceptible to lung tumor induction by chemical… Expand
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Highly Cited
1983
Highly Cited
1983
The cellular oncogene c-Ki-ras is amplified 30- to 60-fold in cells of the mouse adrenocortical tumour Y1. The amplified oncogene… Expand
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Highly Cited
1983
Highly Cited
1983
Analysis of the organization and nucleotide sequence of two human loci related to the transforming gene of Kirsten murine sarcoma… Expand
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