Oncogene ErbB2

Known as: Oncogene, NEU, Oncogene, C-ErbB-2, Oncogene, ERBB2 
Human Oncogene ErbB2 is a mutated variant of ERBB2 Gene, which encodes ERRB2 Receptor Protein Tyrosine Kinase, a 185-kDa type I membrane glycoprotein… (More)
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
BACKGROUND Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that plays an important role in tumor growth and… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that regulates gene expression in critical pathways… (More)
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Highly Cited
2000
Highly Cited
2000
HER-2/neu has been implicated in the activation of androgen receptor (AR) and in inducing hormone-independent prostate cancer… (More)
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Highly Cited
2000
Highly Cited
2000
Determination of HER-2/neu oncogene amplification has become necessary for selection of breast cancer patients for trastuzumab… (More)
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Highly Cited
1994
Highly Cited
1994
Amplification and overexpression of the ERBB2 (HER-2/neu) oncogene has been implicated as contributing to the development of… (More)
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Highly Cited
1994
Highly Cited
1994
BACKGROUND In the United States, prognosis and survival after the diagnosis of breast cancer is poorer among black patients and… (More)
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Highly Cited
1993
Highly Cited
1993
PURPOSE To determine prospectively the prognostic significance of HER-2/neu oncogene amplification in the primary tumors of… (More)
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Highly Cited
1990
Highly Cited
1990
The HER-2/neu proto-oncogene is homologous with, but distinct from, the epidermal growth factor receptor. Current evidence… (More)
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Highly Cited
1989
Highly Cited
1989
Amplification of the HER-2/neu oncogene was recently reported to predict poor clinical outcome in node-positive breast cancer… (More)
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Highly Cited
1987
Highly Cited
1987
The HER-2/neu oncogene is a member of the erbB-like oncogene family, and is related to, but distinct from, the epidermal growth… (More)
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