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Oligonucleotide Synthesis

Known as: Synthesis, Oligonucleotide 
The process of producing oligonucleotides by the union of simpler chemical compounds.
National Institutes of Health

Papers overview

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2013
2013
Direct solid phase synthesis of peptides and oligonucleotides (ONs) requires high chemical stability of the support material. In… Expand
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Highly Cited
2005
Highly Cited
2005
In this paper, we demonstrate in situ synthesis of oligonucleotide probes on poly(dimethylsiloxane) (PDMS) microchannels through… Expand
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2003
2003
Photodirected oligonucleotide synthesis uses either direct or indirect light-dependent 5'-deprotection. Both have been reported… Expand
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Highly Cited
1998
Highly Cited
1998
A new activator for the coupling of phosphoramidites to the 5'-hydroxyl group during oligonucleotide synthesis is introduced. The… Expand
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Highly Cited
1997
Highly Cited
1997
Oligonucleotide dendrimers were synthesized using a novel phosphoramidite synthon, tris-2,2,2-[3-(4,4'-dimethoxytrityloxy… Expand
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1996
1996
  • M. Septak
  • Nucleic acids research
  • 1996
  • Corpus ID: 15815955
Fully protected CPG-immobilized monomer, dimer and trimer oligonucleotides were used to study depurination during the chemical… Expand
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Highly Cited
1992
Highly Cited
1992
A novel linker for the synthesis of oligonucleotides on a glass support is described. Oligonucleotides synthesised on the support… Expand
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Highly Cited
1987
Highly Cited
1987
Tetrazole catalyzed reactions of a series of phosphoramidites, 5'-O-DMTdT-3'-O-P(OR1)NR2(2) (1a-h), with 3'-O-SiButPh2-6-N… Expand
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1986
1986
An effective procedure for the synthesis of oligonucleotides by the phosphotriester method has been developed. The procedure is… Expand
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Highly Cited
1985
Highly Cited
1985
Fluorescent N-/purin-6-yl/pyridinium salts are formed in pyridine assisted phosphorylations and arenesulphonations of the… Expand
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