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Oligonucleotide Synthesis

Known as: Synthesis, Oligonucleotide 
The process of producing oligonucleotides by the union of simpler chemical compounds.
National Institutes of Health

Papers overview

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2013
2013
Interfacing click chemistry with automated oligonucleotide synthesis for the preparation of fluorescent DNA probes containing internal xanthene and cyanine dyes.
Double-labeled oligonucleotide probes containing fluorophores interacting by energy-transfer mechanisms are essential for modern… 
2005
2005
Computer simulation in template-directed oligonucleotide synthesis
SummaryA computer simulation (KINSIM) modeling up to 33 competing reactions was used in order to investigate the product… 
2004
2004
Universal reusable polymer support for oligonucleotide synthesis.
A new efficient reusable universal polymer support for oligonucleotide synthesis, based on a non-ammoniacal cleavable linker, is… 
2003
2003
Novel photoacid generators for photodirected oligonucleotide synthesis.
Photodirected oligonucleotide synthesis uses either direct or indirect light-dependent 5'-deprotection. Both have been reported… 
2003
2003
Novel Photocleavable Universal Support for Oligonucleotide Synthesis
Abstract A novel photocleavable universal support for the automated solid phase synthesis of oligonucleotides is described. The… 
2002
2002
MICROWAVE ASSISTED HIGH YIELDING PREPARATION OF N-PROTECTED 2′-DEOXYRIBONUCLEOSIDES USEFUL FOR OLIGONUCLEOTIDE SYNTHESIS
ABSTRACT A rapid and high yielding method for the synthesis of precursors of synthons for DNA synthesis, N-protected 2… 
1999
1999
Trityl mass-tags for encoding in combinatorial oligonucleotide synthesis.
Combinatorial libraries of oligonucleotides on beads were synthesised by a split-and-mix strategy using 5'-DMTr- or 5'-Fmoc… 
1999
1999
Rapid esterification of nucleosides to solid-phase supports for oligonucleotide synthesis using uronium and phosphonium coupling reagents.
Nucleosides can be esterified to solid-phase supports using uronium or phosphonium coupling reagents and a coupling additive… 
1989
1989
A study on spin-labelled oligonucleotide synthesis and its electron spin resonance behavior in solution.
An oligonucleotide spin-labelled with 4-amino-2,2,6,6-tetramethylpiperidine-N-oxyl (4-amino-TEMPO) at the internucleotide bond (d… 
1986
1986
Application of new catalytic phosphate protecting groups for the highly efficient phosphotriester oligonucleotide synthesis.
An effective procedure for the synthesis of oligonucleotides by the phosphotriester method has been developed. The procedure is… 
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