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ORC4L protein, human

Known as: ORC4L, ORC4 protein, human, ORC4 
Origin recognition complex subunit 4 (436 aa, ~50 kDa) is encoded by the human ORC4 gene. This protein is involved in the replication of DNA.
National Institutes of Health

Related topics

Related topics

12 relations
Cell CycleCell Cycle ControlCell Viability ProcessDNA-Binding Proteins

Broader (2)

Cell Cycle Proteinsorigin recognition complex

Papers overview

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Review
2019
Review
2019
[Phenotypic and genotypic analysis of a girl carrying a 2q22.3 microduplication encompassing the MBD5 gene].
OBJECTIVE To carry out single nucleotide polymorphism (SNP)-based chromosome microarray analysis (CMA) for a boy featuring global… 
2018
2018
Identification of the ORC Complex Subunits That Can Interact with the ENY2 Protein of Drosophila melanogaster
The interaction of the Drosophila ENY2 protein with the ORC complex subunits was investigated. It is found that ORC4 and ORC6… 
2018
2018
The ORC4 Protein: The ORC4 Cage Function in Erythroblast Enucleation
2017
2017
Defective replication initiation results in locus specific chromosome breakage and a ribosomal RNA deficiency in yeast
A form of dwarfism known as Meier-Gorlin syndrome (MGS) is caused by recessive mutations in one of six different genes (ORC1… 
2017
2017
Higher Order Oligomerization of the Licensing ORC4 Protein Is Required for Polar Body Extrusion in Murine Meiosis
We have previously shown that the DNA replication licensing factor ORC4 forms a cage around the chromosomes that are extruded in… 
2016
2016
Meier-Gorlin syndrome genotype-phenotype studies
Meier–Gorlin syndrome (MGS) is an autosomal recessive disorder characterized by microtia, patellar aplasia/hypoplasia, and short… 
2014
2014
ORC4 Plays Another Role Other Than Origin Licensing In The Mouse Zygote
2011
2011
Of ORC and forks: the identification of mutations implicated in Meier‐Gorlin syndrome
References 
2005
2005
Overexpression of ORC subunits and increased ORC‐chromatin association in transformed mammalian cells
The origin recognition complex (ORC) is a conserved heterohexamer required for the formation of pre‐replication (pre‐RC… 
1998
1998
Assignment1 of the homologue of the yeast origin recognition complex subunit ORC4 (ORC4L) to human chromosome band 2q22→q23 by in situ hybridization and somatic cell hybrid analysis
a Cellular Physiology Laboratory, Tsukuba Life Science Center, The Institute of Physical and Chemical Research (RIKEN), Tsukuba… 
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