ORC3 protein, human

Known as: Origin Recognition Complex Subunit 3-Like, Origin Recognition Complex Subunit Latheo, origin recognition complex, subunit 3, human 
Origin recognition complex subunit 3 (711 aa, ~82 kDa) is encoded by the human ORC3 gene. This protein plays a role in the promotion of DNA… (More)
National Institutes of Health

Papers overview

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2007
2007
The engagement of the T-cell receptor (TCR) causes the rapid recruitment of multiple signaling molecules into clusters with the… (More)
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Highly Cited
2003
Highly Cited
2003
Mast cell degranulation and de novo cytokine production is a consequence of antigen-aggregation of the immunoglobulin E (IgE… (More)
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Highly Cited
2002
Highly Cited
2002
Polyunsaturated fatty acids (PUFAs) suppress immune responses and inhibit T cell activation through largely unknown mechanisms… (More)
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Highly Cited
2001
Highly Cited
2001
T-cell-receptor (TCR)-mediated LAT (linker for activation of T cells) phosphorylation is critical for the membrane recruitment of… (More)
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Highly Cited
2000
Highly Cited
2000
The ability of the Src family kinases Fyn and Lck to participate in signaling through the T cell receptor is critically dependent… (More)
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Highly Cited
2000
Highly Cited
2000
The linker molecule LAT is a substrate of the tyrosine kinases activated following TCR engagement of T cells. LAT is also… (More)
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Highly Cited
1999
Highly Cited
1999
The linker molecule LAT is a substrate of the tyrosine kinases activated following TCR engagement. Phosphorylated LAT binds many… (More)
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Highly Cited
1999
Highly Cited
1999
The adaptor molecule LAT (linker for activation of T cells) is a palmitoylated integral membrane protein that localizes to the… (More)
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Highly Cited
1998
Highly Cited
1998
The linker molecule LAT is a critical substrate of the tyrosine kinases activated upon TCR engagement. Phosphorylated LAT binds… (More)
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Highly Cited
1998
Highly Cited
1998
In this study, we present the further characterization of a mutant Jurkat T cell line, J.CaM2, that is defective in TCR-mediated… (More)
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