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OPC 15161

Known as: OPC-15161 
 
National Institutes of Health

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Broader (1)

Pyrazines

Papers overview

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1998
1998
OPC-15161 suppresses the proliferation of Tenon's capsule fibroblasts and the production of type I collagen and fibronectin stimulated by TGF-beta1 in vitro.
PURPOSE We investigated the effects of OPC-15161 on the growth of cultured human Tenon's capsule fibroblasts (TCFs), as well as… Expand
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1998
1998
Inhibitory effect of OPC-15161, a component of fungus Thielavia minor, on proliferation and extracellular matrix production of rat cultured hepatic stellate cells.
A component of fungus Thielavia minor, OPC-15161, has been shown to inhibit the proliferation and extracellular matrix production… Expand
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1998
1998
Fungus thielavia minor blocks hepatic stellate cell proliferation and inhibits experemental hepatic fibrosis in rats
Introdnction and Aim: Hepatic stellate cells (HSCs) are proliferated by cytokines such as PDGF and produce extracellular matrix… Expand
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1997
1997
Therapeutic effect of a newly developed antioxidative agent (OPC-15161) on experimental immune complex nephritis.
The effect of a newly developed free radical scavenger (OPC-15161) on the progression of nephrotoxic serum (NTS) nephritis was… Expand
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1996
1996
The radical scavenging abilities of a new anti-nephritic drug, OPC-15161.
A new anti-nephritic drug, 6-(1H-indol-3-ylmethyl)-5-methoxy-3-(2-methylpropyl)-2-(1H)-pyr azi none 4-oxide (OPC-15161), a… Expand
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1991
1991
Novel inhibitors of superoxide anion generation, OPC-15160 and OPC-15161. Taxonomy, fermentation, isolation, physico-chemical properties, biological characteristics and structure determination.
A new inhibitor of superoxide anion generation by guinea pig macrophages, OPC-15160, was isolated from the culture broth of… Expand
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