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OPC 15161

Known as: OPC-15161 
National Institutes of Health

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Pyrazines

Papers overview

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1998
1998
OPC-15161 suppresses the proliferation of Tenon's capsule fibroblasts and the production of type I collagen and fibronectin stimulated by TGF-beta1 in vitro.
PURPOSE We investigated the effects of OPC-15161 on the growth of cultured human Tenon's capsule fibroblasts (TCFs), as well as… 
1998
1998
Inhibitory effect of OPC‐15161, a component of fungus Thielavia minor, on proliferation and extracellular matrix production of rat cultured hepatic stellate cells
A component of fungus Thielavia minor, OPC‐15161, has been shown to inhibit the proliferation and extracellular matrix production… 
1998
1998
Fungus thielavia minor blocks hepatic stellate cell proliferation and inhibits experemental hepatic fibrosis in rats
1996
1996
The radical scavenging abilities of a new anti-nephritic drug, OPC-15161.
A new anti-nephritic drug, 6-(1H-indol-3-ylmethyl)-5-methoxy-3-(2-methylpropyl)-2-(1H)-pyr azi none 4-oxide (OPC-15161), a… 
1991
1991
Novel inhibitors of superoxide anion generation, OPC-15160 and OPC-15161. Taxonomy, fermentation, isolation, physico-chemical properties, biological characteristics and structure determination.
A new inhibitor of superoxide anion generation by guinea pig macrophages, OPC-15160, was isolated from the culture broth of… 
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