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OP 1206

Known as: OP-1206 
National Institutes of Health

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ONO 1206

Papers overview

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2002
2002
Correlation between methotrexate-induced intestinal damage and decrease in polyamine content.
2001
2001
Protective effect of a synthetic analog of prostaglandin E(1) on the small intestinal damage induced by the administration of methotrexate to rats.
Antitumor drugs like methotrexate cause damage to the small intestine, resulting in malabsorption. The present study evaluated… 
1999
1999
A prostaglandin E1 analog, OP-1206, alleviates 5-fluorouracil-induced injury of rat small intestine.
5-Fluorouracil (5-FU) often causes the gastrointestinal toxicity, including enterocolitis. We investigated effects of OP-1206… 
1997
1997
Analysis of Localization of Adult T-cell Leukemia-derived Factor in the Transient Ischemic Rat Retina After Treatment with OP-1206 α-CD, a Prostaglandin E1 Analogue
Prostaglandin E1 (PGE1) is commonly used in therapy for obstructive diseases, including ischemic retinopathy, in which… 
1996
1996
Effects of OP-1206 (prostaglandin E1) on nerve-conduction velocity in the dog cauda equina subjected to acute experimental compression.
The effect of OP-1206, a prostaglandin E1 derivative, on cauda equina function was analyzed in a model for acute cauda equina… 
1995
1995
OP-1206, a Prostaglandin E1 Derivative, Attenuates the Thermal Hyperesthesia Induced by Constriction Injury to the Sciatic Nerve in the Rat
Nerve ischemia induces wallerian degeneration and peripheral neuropathy, and nerve constriction injury induces thermal… 
1988
1988
Potent inhibition of leukotriene (LT) B4 release from human polymorphonuclear leukocytes (PMN) by the PGE1-analogue OP-1206.
The present study investigates the inhibitory action of the PGE1-analogue OP-1206 on stimulated LTB4 release from human PMN. In… 
1986
1986
Effect of a prostaglandin E1 derivative (OP-1206) and acetylsalicylic acid on electrically induced thrombosis in guinea-pig mesenteric artery and its modification by an inhibitor of prostaglandin I2…
The antithrombotic effect of a prostaglandin E1 derivative, OP-1206 (17S-20-dimethyl-trans-delta 2-PGE1) X alpha-cyclodextrin… 
1984
1984
OP-1206, a prostaglandin E1 derivative. Effects of oral administration to patients with chronic lung disease.
In order to assess the clinical effectiveness of an oral prostaglandin E1 derivative, OP-1206, five patients with chronic… 
1980
1980
Pharmacological evaluation of OP 1206, a prostaglandin E1 derivative, as an antianginal agent.
Effects of OP 1206 were studied on the cardiovascular system and platelet functions to assess OP 1206 as an antianginal agent. OP… 
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