OMP-54F28

Known as: OMP 54F28 
 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (4)

G-Protein-Coupled ReceptorsImmunoglobulin Fc FragmentsIpafriceptRecombinant Fusion Proteins

Papers overview

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2018
2018
Wnt signaling dynamics in head and neck squamous cell cancer tumor-stroma interactions.
Wnt pathway activation maintains the cancer stem cell (CSC) phenotype and promotes tumor progression, making it an attractive… (More)
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2017
2017
A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors.
Purpose: Wnt signaling is implicated in tumor cell dedifferentiation and cancer stem cell function. Ipafricept (OMP-54F28) is a… (More)
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Review
2017
Review
2017
Molecular genetics and targeted therapy of WNT-related human diseases (Review)
Canonical WNT signaling through Frizzled and LRP5/6 receptors is transduced to the WNT/β-catenin and WNT/stabilization of… (More)
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Review
2015
Review
2015
Targeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28.
The Wnt signaling pathways are a group of signal transduction pathways that play an important role in cell fate specification… (More)
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2015
2015
Abstract 4233: Wnt pathway antagonist ipafricept (FZD8-Fc, OMP-54F28) inhibits tumor growth and reduces tumor-initiating cell frequency in ovarian patient-derived xenograft models
 
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