OGG1 gene

Known as: HMMH, OGH1, MUTM 
This gene is involved in base excision repair of oxidatively damaged DNA.
National Institutes of Health

Papers overview

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2008
2008
Oxidative DNA damage is believed to be implicated in lung carcinogenesis. 8-OxodG is a mutagenic and abundant oxidative… (More)
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Highly Cited
2004
Highly Cited
2004
OGG1 protein has an ability to suppress mutagenesis induced by 8-hydroxyguanine (8OHG), an oxidatively damaged promutagenic base… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Germ-line mutations in the base-excision-repair gene MYH have been associated with recessive inheritance of multiple… (More)
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Review
2001
Review
2001
8-Hydroxyguanine (oh8G) is a major base lesion produced by reactive oxygen species. oh8G in DNA causes G:C to T:A transversions… (More)
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Highly Cited
1999
Highly Cited
1999
We identified seven alternatively spliced forms of human 8-oxoguanine DNA glycosylase (OGG1) mRNAs, classified into two types… (More)
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Highly Cited
1998
Highly Cited
1998
The human OGG1 gene encodes a DNA glycosylase activity catalysing the excision of the mutagenic lesion 7,8-dihydro-8-oxoguanine… (More)
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Highly Cited
1997
Highly Cited
1997
The OGG1 gene of Saccharomyces cerevisiae encodes a DNA glycosylase activity that is a functional analog of the Fpg protein from… (More)
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Highly Cited
1997
Highly Cited
1997
We report the cloning of a human homolog of the yeast OGG1 gene, which encodes a DNA glycosylase that excises an oxidatively… (More)
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Highly Cited
1997
Highly Cited
1997
Reactive oxygen species can damage most cellular components, but DNA appears to be the most sensitive target of these agents… (More)
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Highly Cited
1997
Highly Cited
1997
The OGG1 gene of Saccharomyces cerevisiae encodes a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine (8-OxoG) and 2,6… (More)
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