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O-acetylhomoserine (thiol)-lyase activity

Known as: L-methionine formation, direct, from O-acetyl-L-homoserine, O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase activity, L-methionine synthesis, direct, from O-acetyl-L-homoserine 
Catalysis of the reaction: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate. Also reacts with other thiols and H2S, producing… 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
A thermochromic silver nanocluster exhibiting dual emission character.
A Ag12(SCH2C10H7)6(CF3CO2)6(CH3CN)6 (1) nanocluster modified using naphthalen-2-yl-methanethiol was synthesized and structurally… 
2010
2010
Towards methionine overproduction in Corynebacterium glutamicum--methanethiol and dimethyldisulfide as reduced sulfur sources.
In the present work, methanethiol and dimethyldisulfide were investigated as sulfur source for methionine synthesis in… 
2003
2003
In vivo analysis of various substrates utilized by cystathionine gamma-synthase and O-acetylhomoserine sulfhydrylase in methionine biosynthesis.
To gain insight into the evolution of the methionine biosynthesis pathway, in vivo complementation tests were performed. The… 
Highly Cited
1999
Highly Cited
1999
Molecular cloning and functional expression of a human peptide methionine sulfoxide reductase (hMsrA)
1975
1975
Purification and properties of homoserine transacetylase from Bacillus polymyxa.
1975
1975
Comparative metabolism of L-methionine and N-acetylated derivatives of methionine.
These experiments compared the metabolism of the N-acetylated derivatives of D- or L-methionine to that of L-methionine. Spargue… 
1973
1973
Studies on beta-cystathionase and omicron-acetylhomoserine sulfhydrylase as the enzymes of alternative methionine biosynthetic pathways in Aspergillus nidulans.
1971
1971
The enzymic formation of O-acetylhomoserine in Bacillus subtilis and its regulation by methionine and S-adenosylmethionine.
Highly Cited
1970
Highly Cited
1970
Hydrogen sulphide production by yeast under conditions of methionine, pantothenate or vitamin B6 deficiency.
  • T. Wainwright
  • Journal of General Microbiology
  • 1970
  • Corpus ID: 31762464
SUMMARY: Methionine-requiring mutants of Saccharomyces cerevisiae produce large amounts of hydrogen sulphide from sulphate… 
Highly Cited
1967
Highly Cited
1967
Acyl derivatives of homoserine as substrates for homocysteine synthesis in Neurospora crassa, yeast, and Escherichia coli.
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