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O(6)-n-butylguanine

Known as: O(6)-butylguanine 
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
The tobacco specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a potent pulmonary carcinogen, both… Expand
1994
1994
N-Nitrosobutyl(4-hydroxybutyl)amine (BBN) is a selective bladder carcinogen in rats. Its organ specificity may depend on several… Expand
1993
1993
The mutagenic activity of a series of longer chain O6-n-alkylguanine residues (O6-n-propyl, O6-n-butyl, O6-n-octyl) has been… Expand
1990
1990
A sensitive, specific, and rapid method for quantitating the minor adduct O6-butylguanine (O6BuG) in hydrolyzed DNA has been… Expand
Highly Cited
1986
Highly Cited
1986
Two human colon carcinoma cell lines which differ greatly in their content of O6-alkylguanine-DNA alkyltransferase were analyzed… Expand
Highly Cited
1985
Highly Cited
1985
Exposure of HeLa cells to 0.2 mM O6-methylguanine for 4 h or longer led to a 70-80% loss in the activity of the DNA-repair… Expand
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Highly Cited
1985
Highly Cited
1985
DNA substrates containing O6-n-butylguanine, O6-iso-butylguanine, O6-n-propylguanine and O6-iso-propylguanine were prepared by… Expand
Highly Cited
1985
Highly Cited
1985
Exposure of HeLa S3 cells to 0.4mM 0(6)-methylguanine or 0(6)-n-butylguanine for 24 h led to a substantial decrease in the… Expand
1985
1985
Using site-specific mutagenesis, we have examined the mutagenic activity in vivo of O6-methylguanine or O6-n-butylguanine located… Expand
1980
1980
N-n-[1-14C]Butyl-N-nitrosourea was synthesized from n-[1-14C]butanol and incubated at physiological conditions (pH 7.2; 37… Expand